Protective effect of Kombucha tea on brain damage induced by transient cerebral ischemia and reperfusion in rat

Kabiri, najmeh. and Setorki, Mahbubeh. (2016) Protective effect of Kombucha tea on brain damage induced by transient cerebral ischemia and reperfusion in rat. Bangladesh Journal of Pharmacology, 11 (3). pp. 675-683.

[img]
Preview
Text
16.pdf

Download (689kB) | Preview
Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

The aim of study was to investigate the potential neuroprotective effects of Kombucha on cerebral damage induced by ischemia in rats (n=99). Cerebral infarct volume in the ischemic rats received Kombucha solution showed no significance alteration. However, the permeability of blood-brain barrier significantly decreased in both ischemic rats received 15 mg/kg Kombucha tea and Sham group. In addition, brain water content in the ischemic groups treated with Kombucha solution was significantly higher than the Sham group, although right hemispheres in all of the treated groups illustrated higher brain water content than the left ones. Brain anti-oxidant capacity elevated in the ischemic rats treated with Kombucha and in the Sham group. Brain and plasma malondialdehyde concentrations significantly decreased in both of the ischemic groups injected with Kombucha. The findings suggest that Kombucha tea could be useful for the prevention of cerebral damage. © 2016, Bangladesh Pharmacological Society. All rights reserved.

Item Type: Article
Additional Information: cited By 1
Uncontrolled Keywords: Brain damage, Kombucha tea, Rat, Reperfusion, Transient cerebral ischemia
Subjects: WL Nervous system
QV pharmacology > QV 752 Pharmacognosy
Divisions: Faculty of Medicine
Depositing User: Users 1 not found.
Date Deposited: 11 Jul 2017 04:46
Last Modified: 06 Mar 2018 10:04
URI: http://eprints.skums.ac.ir/id/eprint/950

Actions (login required)

View Item View Item