Prevalence and determinants of anemia among Iranian population aged ≥35 years: A PERSIAN cohort–based cross-sectional study

Ashktorab, Hassan and Zamani, Mohammad and Poustchi, Hossein and Shayanrad, Amaneh and Pourfarzi, Farhad and Farjam, Mojtaba and Noemani, Kourosh and Ghaderi, Ebrahim and Mohammadkarimi, Vahid and Kahnooji, Mahmood and Mansour-Ghanaei, Fariborz and Rastegar, Ayoob and Mousavizadeh, Ali and Rafati, Shideh and Johari, Masoumeh Ghoddusi and Moosazadeh, Mahmood and Salehifardjouneghani, Alizamen and Ostadrahimi, Alireza and Mohebbi, Iraj and Khorram, Alireza and Ardakani, Fatemeh Ezzodini and Sharafkhah, Maryam and Pasdar, Yahya and Sadeghi, Anahita and Malekzadeh, Reza (2022) Prevalence and determinants of anemia among Iranian population aged ≥35 years: A PERSIAN cohort–based cross-sectional study. PLOS ONE, 17 (2). e0263795. ISSN 1932-6203

Full text not available from this repository.
Official URL:


Background So far, no comprehensive studies have been performed to assess burden and determinants of anemia in Iran. In the present study, we aimed to answer this query using the data obtained from the Prospective Epidemiological Research Studies in IrAN (PERSIAN). Methods In this cross-sectional study, we included 161,686 adult participants (aged 35 years and older) from 16 provinces of Iran. Anemia was defined as a hemoglobin concentration of <13 g/dL in males and <12 g/dL in females. To evaluate the association between anemia and different factors, we used the multivariable Poisson regression analysis with robust variance by applying adjusted prevalence ratio (PR) with 95% confidence interval (CI). Results Of the total number of subjects, 72,387 (44.77%) were male and others were female. Mean age was 49.39±9.15 years old. The overall age- and sex-standardized prevalence of anemia was 8.83% (95% CI: 8.70–8.96%) in the included population. The highest and the lowest age- and sex-standardized prevalence of anemia pertained to Hormozgan (37.41%, 95% CI: 35.97–38.85%) and Kurdistan (4.57%, 95% CI: 3.87–5.27%) provinces, respectively. Being female (PR = 2.97), rural residence (PR = 1.24), being retired (PR = 1.53) and housewife (PR = 1.11), third and fourth wealth status quartiles (PR = 1.09 and PR = 1.11, respectively), being underweight (PR = 1.49), drug user (PR = 1.35), inadequate sleep (PR = 1.16), poor physical activity (PR = 1.15), diabetes (PR = 1.09), renal failure (PR = 2.24), and cancer (PR = 1.35) were associated with increased risk of anemia. On the other hand, illiteracy (PR = 0.79) and abdominal obesity (PR = 0.77) decreased the risk of anemia. Conclusions According to the results, a variable prevalence of anemia was observed across the included provinces. We tried to provide an informative report on anemia prevalence for health professionals and authorities to take measures for identification and management of the cases of anemia in high-prevalence areas.

Item Type: Article
Subjects: WH Hemic and Lymphatic System
Divisions: Reserach Vice-Chancellar Department > Modeling in Health Research Center
Depositing User: zeynab . bagheri
Date Deposited: 16 Mar 2022 06:25
Last Modified: 16 Mar 2022 06:25

Actions (login required)

View Item View Item