Baseline Characteristics and Associated Factors of Mortality in COVID-19 Patients; an Analysis of 16000 Cases in Tehran, Iran

Zali, Alireza and Gholamzadeh, Saeid and Mohammadi, Gohar and Looha, Mehdi Azizmohammad and Akrami, Forouzan and Zarean, Elaheh and Vafaee, Reza and Maher, Ali and Khodadoost, Mahmood (2020) Baseline Characteristics and Associated Factors of Mortality in COVID-19 Patients; an Analysis of 16000 Cases in Tehran, Iran. Archives of Academic Emergency Medicine, 8 (1). pp. 1-12. ISSN 26454904

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Introduction: Given the importance of evidence-based decision-making, this study aimed to evaluate epidemiological and clinical characteristics as well as associate factors of mortality among admitted COVID-19 cases. Methods: This multicenter, cross-sectional study was conducted on confirmed and suspected COVID-19 cases who were hospitalized in 19 public hospitals affiliated to Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran, between February 19 and May 12, 2020. Epidemiological and clinical characteristics of the infected cases were compared between the deceased and survivors after discharge. Case fatality rates (CFRs) were calculated across all study variables. Single and multiple logistic regressions were used to explore the risk factors associated with COIVD-19 mortality. Results: Out of the 16035 cases that referred to the hospitals affiliated to SBMU, 16016 patients (99.93 of Confirmed and 99.83 of suspected cases) were hospitalized. 1612 patients died with median hospitalization days of 5 (interquartile range (IQR): 2-9) and 3 (1-7) for confirmed and suspected COVID-19 cases, respectively. The highest death rate was observed among ages>65 (63.4 of confirmed cases, 62.3 of suspected cases) and intensive care unit (ICU)/critical care unit (CCU) patients (62.7 of confirmed cases, 52.2 of suspected cases). Total case fatality rate (CFR) was 10.05 (13.52 and 6.37 among confirmed and suspected cases, respectively). The highest total CFR was observed in patients with age>65 years (25.32), underlying comorbidities (25.55), and ICU/CCU patients (41.7). The highest CFR was reported for patients who had diabetes and cardiovascular diseases (38.46) as underlying non-communicable diseases (NCDs), and patients with cancer (35.79). Conclusion: This study showed a high CFR among suspected and confirmed COVID-19 cases, and highlighted the main associated risk factors including age, sex, underlying NCDs, and ICU/CCU admission affecting survival of COVID-19 patients © 2020, Archives of Academic Emergency Medicine. All Rights Reserved.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: adult; age distribution; aged; Article; cardiovascular disease; comorbidity; computer assisted tomography; controlled study; coronavirus disease 2019; cross-sectional study; diabetes mellitus; disease association; female; high risk patient; hospitalization; human; hypertension; intensive care unit; Iran; length of stay; major clinical study; male; malignant neoplasm; mortality rate; non communicable disease; polymerase chain reaction; prevalence; risk factor; Severe acute respiratory syndrome coronavirus 2; sex difference; survival rate; survival time; thorax radiography
Subjects: WC Communicable Diseases
WC Communicable Diseases > Virus diseases
Divisions: Reserach Vice-Chancellar Department > Modeling in Health Research Center
Depositing User: zeynab . bagheri
Date Deposited: 21 Feb 2021 09:40
Last Modified: 21 Feb 2021 09:40

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