The potential association between metabolic syndrome and risk of post-surgical adhesion

Ferns, Gordon A and Shahini Shams Abadi, Milad and Arjmand, Mohammad-Hassan (2020) The potential association between metabolic syndrome and risk of post-surgical adhesion. Archives of Physiology and Biochemistry. pp. 1-6. ISSN 1381-3455

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Metabolic syndrome (MetS) is defined by the clustering of several associated with a group of disorders that include: obesity, dyslipidemia, hypertension, and insulin resistance. The incidence of MetS is increasing globally around the world. Indeed the rates of different types of surgery in older or younger patients with Mets are increasing and they are exposed to a wide range of operations including abdominal, pelvic, urologic, or any invasive procedures. Post-surgical adhesion is a common problem and is a challenge for the surgeon. Despite many studies on its pathogenesis, there remain many un-answered questions about it, for example why certain tissues and patients are more at higher risk of post-surgical adhesions. Many studies have suggested that MetS is associated with up-regulating molecular mechanisms leading to chronic inflammation and hypercoagulability. In this review, we discuss some of the molecular mechanisms by MetS may enhance post-surgical adhesion, and particularly regarding those involved in coagulation and inflammation.

Item Type: Article
Subjects: WD Nutrition Disease and metabolic diseases
Divisions: Reserach Vice-Chancellar Department > Cellular and Molecular Research Center
Depositing User: zeynab . bagheri
Date Deposited: 27 Dec 2020 04:57
Last Modified: 27 Dec 2020 04:57

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