Curcumin: footprints on cardiac tissue engineering

Kargozar, Saeid and Baino, Francesco and Hoseini, Seyed Javad and Verdi, Javad and Asadpour, Shiva and Mozafari, Masoud (2019) Curcumin: footprints on cardiac tissue engineering. Expert Opinion on Biological Therapy, 19 (11). ISSN 14712598

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Introduction: Curcumin-based products are extensively used as therapeutics in the treatment of cardiac disorders; however, there is no significant report on the curcumin potentials in cardiac tissue engineering applications. Due to its anti-oxidant, anti-inflammatory, and anti-apoptotic properties, curcumin has been demonstrated to be a promising candidate for tissue engineering (TE) applications. Areas covered: Various curcumin-containing tissue-engineered constructs have been developed for the management of soft tissue damages (such as wound injuries); hence, there are hopes for the use of this natural product in cardiac tissue engineering (CTE). However, some crucial issues should primarily be addressed before curcumin could be widely used in CTE. Expert opinion: The challenges regarding the use of curcumin in CTE include the optimum dosages of curcumin for promoting cardiac regeneration, the type of carrier used (e.g., polymeric matrices), the preferable release profile, as well as the short- and long-term toxicity in the human body. keywords: biomaterialscardiac patchescardiac tissue engineeringCurcuminregenerative medicinescaffoldstissue engineering

Item Type: Article
Subjects: WG Cardiovascular System
Divisions: Faculty of Advanced Technologies > Department of Tissue Engineering
Depositing User: zeynab . bagheri
Date Deposited: 10 May 2020 07:12
Last Modified: 02 Jun 2020 06:02

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