Comparative study of the effect of Thymus daenensis gel 5% and diclofenac in patients with knee osteoarthritis.

Dehghan, Morteza and Asgharian, Shirin and Khalesi, Elena and Ahmadi, Ali and Lorigooini, Zahra (2019) Comparative study of the effect of Thymus daenensis gel 5% and diclofenac in patients with knee osteoarthritis. Biomedicine. ISSN 2211-8039

[img]
Preview
Text
bmdcn2019090209.pdf - Published Version

Download (1MB) | Preview

Abstract

BACKGROUND: Osteoarthritis is a syndrome characterized by joint pain and reduced performance and efficien- cy in patient. Thymus daenensis has been used since old times for the treatment of bone and joint deformities and pain in traditional medicine. PURPOSE: This study was conducted to examine traditional usages and pharmacological features of T. daen- ensis with respect to the effect of the plant in patients with osteoarthritis. METHODS: 120 patients with osteoarthritis were divided into 3 groups. Patients in each group were treated by 5% Thymus daenensis gel, 1% diclofenac gel, or placebo for 6 weeks, along with oral celecoxib capsules. Patients were assessed in different intervals, based on the VAS score for assessment of pain in the joint and different dimensions of WOMAC questionnaire. RESULTS: Pain level (P < 0.005), stiffness during the day (P < 0.05), morning stiffness (P < 0.05) and physi- cal performance (P < 0.05) were significantly different among the groups. CONCLUSIONS: Thymus daenensis gel improves the symptoms in patients equal and without significant difference than diclofenac group. It can be argued that its use can produce a satisfactory effect on patients with osteoarthritis due to its low cost, easy access, the plant's natively occurring in Iran.

Item Type: Article
Subjects: WE Musculoskeletal system
Divisions: Reserach Vice-Chancellar Department > Medical Plants Research Center
Depositing User: marzieye nazari .
Date Deposited: 22 Sep 2019 10:27
Last Modified: 22 Sep 2019 10:27
URI: http://eprints.skums.ac.ir/id/eprint/7916

Actions (login required)

View Item View Item