Improving effects of green tea on renal nephrotoxicity

Nasri, H. and Khodadadi, S. and Moradi, M. and Ahmadi, A. and Kohi, G. and Rafieian-Kopaei, M. (2016) Improving effects of green tea on renal nephrotoxicity. Journal of Isfahan Medical School, 34 (385). pp. 642-648.

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Abstract

Contrast media-induced acute renal damage could lead to renal failure; so, recently much attention has been made on the efficacy of medicinal plants in prevention and treatment of various diseases, especially in kidney and liver complications. Methods: Forty rats were randomly divided into four groups of 10 consisting of control, contrast media, contrast media plus green tea and green tea pretreatment and contrast media group, respectively. After collecting blood samples from lateral tail vein blood urea nitrogen (BUN) and serum creatinine were measured for assessing tubular nephrotoxicity. Findings: In the second group creatinine level was significantly higher than other groups (P ≤ 0.05). Conclusion: Green tea can provide an applicable intervention approach in individuals with a risk for contrast induced acute kidney injury. So, further preclinical investigations are necessary to confirm the efficiency of this herb against various injurious substances to the renal tubular cells.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: Acute kidney injuryو Contrast mediaو Green teaو Medicinal plantsو Toxicity
Subjects: WJ Urogenital System
QV pharmacology > QV 752 Pharmacognosy
Divisions: Reserach Vice-Chancellar Department > Medical Plants Research Center
Depositing User: zahra bagheri .
Date Deposited: 04 Jul 2017 05:44
Last Modified: 04 Jul 2017 05:44
URI: http://eprints.skums.ac.ir/id/eprint/743

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