Tobacco consumption, opium use, alcohol drinking and the risk of esophageal cancer in North Khorasan, Iran

Pournaghi, Seyed-Javad and Hojjat, Seyed Kaveh and Noveyri, Farhad Barazandeh and Ghouchani, Hamid Tavakkoli and Ahmadi, Ali and Hamedi, Andishe (2018) Tobacco consumption, opium use, alcohol drinking and the risk of esophageal cancer in North Khorasan, Iran. JOURNAL OF SUBSTANCE USE, 24 (1).

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Abstract

Background: There are some unique epidemiological characteristics of esophageal cancer in Iran. The objective of this study was finding the association between tobacco, substance and alcohol using with the risk of esophageal cancer in North Khorasan, Iran. Methods: This Case-Control study was carried out on 96 patients with esophageal cancer and 187 controls. Controls were matched to cases by age and sex. Data were collected through structured interview. Data were analyzed by using chi-square test, T-test and logistic regression, in Stata software version 12. Results: Our findings show Hookah smoking [OR = 6.1(CI95%:1.2-13.1)] and opium consumption [OR = 2.1(CI95%:1.2-3.5)] were associated with esophageal cancer. Cigarette and pipe smoking, age of onset of smoking, duration of smoking, number of smoking per day, leaving history of smoking, years of leaving smoking, drug withdrawal, number of times of drug withdrawal, a history of drug relapse, alcohol consumption and alcohol dose-response were not related to esophageal cancer. Conclusion: According to our results, hookah smoking and opium consumption enhance the risk of esophageal cancer in North Khorasan of Iran. We suggest appropriate planning to prevent the esophageal cancer in this district.

Item Type: Article
Uncontrolled Keywords: SQUAMOUS-CELL CARCINOMA, SMOKING, METAANALYSIS, POPULATION, BURDEN, COHORT
Subjects: WL Nervous system
QZ pathology-Neoplasms
QV pharmacology
Divisions: Faculty of Medicine
Depositing User: Unnamed user with email zamani.m@skums.ac.ir
Date Deposited: 28 Nov 2018 11:08
Last Modified: 23 Apr 2019 03:38
URI: http://eprints.skums.ac.ir/id/eprint/7405

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