The relationship between vitamin D deficiency and metabolic syndrome in obese individuals

Mirhoseini, Mahmood and Daemi, Hamid and Babaiee, Mahshid Masoom and Asadi-Samani, Majid and Mirhoseini, Leilaassadat and Sedehi, Morteza (2018) The relationship between vitamin D deficiency and metabolic syndrome in obese individuals. JOURNAL OF RENAL INJURY PREVENTION, 7 (4).

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Abstract

Introduction: Decreased vitamin D levels may have a role in the development of metabolic syndrome due to its effect on the metabolic syndrome components or because of insulin resistance. Objectives: The aim of this study was to investigate the prevalence of vitamin D deficiency in obese individuals and to determine the relationship between deficiency of vitamin D with metabolic syndrome in obese people with metabolic syndrome and healthy individuals. Patients and Methods: In this descriptive-analytical study, samples were selected among obese individuals admitted to Hajar and Kashani hospitals in Shahrekord. Metabolic indices of the samples were measured and recorded along with information such as demographic characteristics. According to the indices, the subjects (n=192) were divided into two equal groups of healthy obese and obese people with metabolic syndrome. Vitamin D levels were measured in both groups followed by determination of relationships between the vitamin D levels with metabolic syndrome and its indices. Results: The mean ages of the patients and healthy groups were 50.09 +/- 1.95 years and 52.57 +/- 2.05 years, respectively. The average serum vitamin D levels in the two groups showed a significant difference with significantly lower vitamin D levels in the metabolic syndrome group than those in the obese subjects (P < 0.001). The relationship between each of the metabolic syndrome indices at different levels of vitamin D showed that levels of triglyceride (TG) and fasting blood sugar (FBS) decreased with increasing serum vitamin D. However, the level of vitamin D was not significantly related to the waist size and body mass index (BMI) (P > 0.05).

Item Type: Article
Uncontrolled Keywords: CARDIOVASCULAR RISK, 25-HYDROXYVITAMIN D, INSULIN-RESISTANCE, PREVALENCE, ASSOCIATION, ADULTS
Subjects: WD Nutrition Disease and metabolic diseases
QU Biochemistry
Divisions: Faculty of Health
Depositing User: Unnamed user with email nazari@skums.ac.ir
Date Deposited: 11 Nov 2018 06:13
Last Modified: 22 Apr 2019 08:11
URI: http://eprints.skums.ac.ir/id/eprint/7339

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