The Effectiveness of Melissa officinalis on Sleep Problem in Patients with Chronic Heart Failure

Aliakbari, Fatemeh and Rafieian, Mahmoud (2018) The Effectiveness of Melissa officinalis on Sleep Problem in Patients with Chronic Heart Failure. JOURNAL OF PHARMACEUTICAL NEGATIVE RESULTS, 9 (1).


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Background: Numerous studies have documented high prevalence rate of major depression in patients with heart failure. The aim of the present study was to evaluate the effectiveness of Melissa officinalis on sleep problem in patients with chronic heart failure (CHF). Materials and Methods: In a randomized, controlled trial study, eighty patients (40 in each group) with CHF experiencing insomnia were allocated randomly into intervention and control groups. The patients in intervention group received 12 ml M. officinalis syrup in addition to conventional treatment 1 h before going to bed for 4 weeks. A demographic questionnaire and the Pittsburgh Sleep Quality Index were used to collect data. Questionnaires were completed by all individuals before and after the intervention. Results: The time duration of waiting for falling into sleep in intervention group was significantly less than control group (P = 0.001). The hours during which the individuals were fully asleep were significantly more than control group (P < 0.05). Conclusion: M. officinalis may improve the quality of sleep in patients with CHF who experience insomnia.

Item Type: Article
Uncontrolled Keywords: Heart failure, Melissa officinalis, sleep
Subjects: WG Cardiovascular System
WM Psychiatry
Divisions: Faculty of Medicine
Depositing User: Unnamed user with email
Date Deposited: 23 Sep 2018 06:06
Last Modified: 23 Sep 2018 06:06

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