Clinical evaluation of blood pressure lowering, endothelial function improving, hypolipidemic and anti‐inflammatory effects of pomegranate juice in hypertensive sub

Asgary, Sedigheh. and Sahebkar, Amirhossein. and Afshani, Mohammad Reza. and Keshvari, Mahtab. and Haghjooyjavanmard, Shaghayegh. and Rafieian-Kopaei, Mahmoud. (2014) Clinical evaluation of blood pressure lowering, endothelial function improving, hypolipidemic and anti‐inflammatory effects of pomegranate juice in hypertensive sub. Phytotherapy Research, 28 (2).

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Abstract

Abstract Pomegranate (Punica granatum L.) juice (PJ) contains different types of antioxidants and bioactive polyphenols and has been reported to promote cardiovascular health through several mechanisms. The present study aimed to examine the effects of 2- week intake of fresh PJ on blood pressure, flow-mediated dilatation (FMD), serum lipid profile and concentrations of inflammatory and endothelial function biomarkers. Twenty-one hypertensive patients (aged 30–67 years) were recruited into the trial and assigned to receive either PJ (150 ml/day in a single occasion between lunch and dinner; n= 11) or the same amount of water (n= 10) for a period of 2 weeks. Systolic (SBP) and diastolic (DBP) pressures together with FMD and serum concentrations of lipid profile parameters, apolipoproteins A and B, intracellular adhesion molecule-1 (ICAM-1), vascular...

Item Type: Article
Uncontrolled Keywords: blood pressure; atherosclerosis; alternative medicine; pro-inflammatory cytokines.
Subjects: WG Cardiovascular System
QU Biochemistry > Nutrition.vitamins
QV pharmacology > QV 752 Pharmacognosy
Divisions: Reserach Vice-Chancellar Department > Medical Plants Research Center
Depositing User: zahra bagheri .
Date Deposited: 21 Jan 2018 10:03
Last Modified: 29 May 2018 10:15
URI: http://eprints.skums.ac.ir/id/eprint/6885

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