Oxidative stress and Parkinson’s disease: new hopes in treatment with herbal antioxidants

Sarrafchi, Amir. and Bahmani, Mahmoud. and shirzad, Hedayatollah. and Rafieian-Kopaei, Mahmoud. (2016) Oxidative stress and Parkinson’s disease: new hopes in treatment with herbal antioxidants. Current pharmaceutical design, 22 (2).


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Parkinson's disease (PD) is a neurodegenerative disorder due to dopamine deficit in substatia nigra. PD is mainly a sporadic disease with unestablished etiology. However, exposure to environmental toxins, head trauma, inflammation, and free radicals are potential reasons. Recently, the role of oxidative stress in neurological abnormalities, including PD, has been particularly addressed. Antioxidant remedies, particularly herbal antioxidants, have revealed new perspectives of research and therapy as possible preventive and therapeutic approaches for PD. In this paper, we reviewed the recently published papers on the effects of herbal medicines on PD alongside the pathogenesis of PD with regard to oxidative stress.

Item Type: Article
Uncontrolled Keywords: Antioxidant, Degenerative disorder, Herbal medicines, Medicinal plants, Oxidative stress, Parkinson's disease.
Subjects: WL Nervous system
QV pharmacology > QV 752 Pharmacognosy
Divisions: Reserach Vice-Chancellar Department > Cellular and Molecular Research Center
Reserach Vice-Chancellar Department > Medical Plants Research Center
Depositing User: Users 1 not found.
Date Deposited: 21 Jan 2018 09:29
Last Modified: 03 Jun 2018 05:24
URI: http://eprints.skums.ac.ir/id/eprint/6881

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