Secondary Hyperparathyroidism in chronic kidney disease patients; current knowledge

Amiri, M. and Nasri, H. (2006) Secondary Hyperparathyroidism in chronic kidney disease patients; current knowledge. Minerva Urol Nefrol, 58 (4).

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Abstract

When renal function diminishes, secondary hyperparathyroidism with develop in response to worsening of kidney function and declined phosphate excretion (1). Dysregulation of phosphorous and calcium homeostasis leads to decreased kidney phosphate excretion, raised serum phosphorous, reduced synthesis of calcitriol, and elevated levels of the phosphatonin fibroblast growth factor 23 (FGF-23)(2-4). These alterations result in parathyroid hyperplasia and enhanced synthesis and secretion of parathyroid hormone …

Item Type: Article
Subjects: WJ Urogenital System
WK Endocrine System
Divisions: Reserach Vice-Chancellar Department > Social Determinants of Health Research Center
Depositing User: Users 1 not found.
Date Deposited: 16 Jan 2018 07:24
Last Modified: 16 Jan 2018 07:25
URI: http://eprints.skums.ac.ir/id/eprint/6852

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