Cohort-specific trends in stroke mortality in seven European countries were related to infant mortality rates

Amiri, Masoud. and Kunst, Anton. and Janssen, Fanny. and Mackenbach, Johan. (2006) Cohort-specific trends in stroke mortality in seven European countries were related to infant mortality rates. Journal of clinical epidemiology, 59 (12).


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Objectives: To assess, in a population-based study, whether secular trends in cardiovascular disease mortality in seven European countries were correlated with past trends in infant mortality rate (IMR) in these countries. Study Design and Setting: Data on ischemic heart disease (IHD) and stroke mortality in 1950e1999 in the Netherlands, England & Wales, France, and four Nordic countries were analyzed. We used Poisson regression to describe trends in mortality according to birth cohort, for the cohorts born between 1860 and 1939. Pearson correlation coefficients were calculated to determine associations between IMR and IHD, or stroke mortality. Results: IHD mortality increased for successive cohorts up to 1900, and then started to decline. Stroke mortality levels were virtually stable among birth cohorts up to 1880, but declined rapidly among later cohorts. A strong positive association was found between cohortspecific IMR levels and stroke mortality rates. There were no strong cohort-wise associations between IMR and IHD mortality. Conclusion: These results support other studies in suggesting that living conditions in early childhood may influence population levels of stroke mortality. Future studies should determine the contribution of specific early life factors to the mortality decline in IHD and especially stroke.

Item Type: Article
Uncontrolled Keywords: Europe; Mortality trends; Ischemic heart disease; Stroke; Cohort analysis; Infant mortality rate
Subjects: WG Cardiovascular System
WL Nervous system
Divisions: Reserach Vice-Chancellar Department > Social Determinants of Health Research Center
Depositing User: Users 1 not found.
Date Deposited: 16 Jan 2018 06:40
Last Modified: 11 Jun 2018 04:43

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