Evaluation of endothelial and inducible nitric oxide synthase genes expression in the heart of broiler chickens with experimental pulmonary hypertension

Hassanpour, Hossein. and Yazdani, A. and Khabir Soreshjani, K. and Asgharzadeh, Samira. (2009) Evaluation of endothelial and inducible nitric oxide synthase genes expression in the heart of broiler chickens with experimental pulmonary hypertension. British poultry science, 50 (6).

Full text not available from this repository.

Abstract

1. To clarify the effect of cold-induced pulmonary hypertension on endothelial and inducible nitric oxide synthase (eNOS and iNOS) mRNA expression in the lung of broiler chickens, semi quantitative reverse transcription-PCR was performed on total RNAs isolated from lungs of the broiler chickens exposed to 5 weeks of cold stress. 2. The eNOS gene was expressed increasingly with the increasing age during the rearing period. 3. Comparing the treatment group with its related control group eNOS was expressed significantly only at d 21. 4. Expression of iNOS mRNA also increased in both control and treatment groups with increasing age until d 28 and then decreased at d 35 and 42. 5. Comparing the treatment group with its control group, iNOS mRNA level was significantly higher at 21 d of age in the cold-exposed chickens. 6. It was concluded that, although cold exposure could significantly increase eNOS and iNOS gene expression, cold-induced pulmonary hypertension is not associated with significant variations of eNOS and iNOS expression in the lungs of broiler chickens.

Item Type: Article
Subjects: QU Biochemistry
QU Biochemistry > Cell biology and genetics
Divisions: Reserach Vice-Chancellar Department > Cellular and Molecular Research Center
Depositing User: Users 1 not found.
Date Deposited: 10 Dec 2017 06:56
Last Modified: 24 Apr 2018 08:39
URI: http://eprints.skums.ac.ir/id/eprint/6520

Actions (login required)

View Item View Item