Inhibitory effects of β-cyclodextrin and trehalose on nanofibril and AGE formation during glycation of human serum albumin

Sharifi, Esmaeel. and Sattarahmady, Naghmeh. and Habibi-Rezaei, Mehran. and Farhadi, Mohammad. and Sheibani, Nader. and Ahmad, Faizan. and Moosavi Movahedi, Aliakbar. (2009) Inhibitory effects of β-cyclodextrin and trehalose on nanofibril and AGE formation during glycation of human serum albumin. Protein and peptide letters, 16 (6).

[img]
Preview
Text
2015.pdf

Download (1MB) | Preview

Abstract

The effects of β-cyclodextrin (β-CyD) and trehalose on glycation of human serum albumin (HSA) were studied. These additives reduced AGEs and nanofibril formation of HSA under in vitro glycation conditions and improved its helical structure. These were accomplished through direct interactions of them with HSA and alterations in solute-protein interactions.

Item Type: Article
Subjects: QU Biochemistry
Divisions: Reserach Vice-Chancellar Department > Cellular and Molecular Research Center
Depositing User: Users 1 not found.
Date Deposited: 22 Nov 2017 09:03
Last Modified: 19 May 2018 08:42
URI: http://eprints.skums.ac.ir/id/eprint/6404

Actions (login required)

View Item View Item