DFNB59 Gene Mutation Screening Using PCR-SSCP/HA Technique in Non-syndromic Genetic Hearing Loss in Bushehr Province

Azadegan-Dehkordi, Fatemeh. and Farrokhi, Effat. and Montazer Zohouri, Mostafa. and Mobini, Gholam Reza. and Taherzadeh Ghahfarrokhi, Maryam. and Raiesi, Marzieh. and Raiesi, Somayeh. and Banitalebi, Mehdi. and Hashemzadeh-Chaleshtori, Morteza. and Soleimani, Mahshid. and kasiri, mahboobeh. and Shirmardi, Seyed Abolfath. and Taji, Fatemeh. and Asgari, Azam. and Banitalebi, Golandam. and safari, javad. (2010) DFNB59 Gene Mutation Screening Using PCR-SSCP/HA Technique in Non-syndromic Genetic Hearing Loss in Bushehr Province. ISMJ, 13 (3).

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Abstract

Background: Hearing impairment (HI) is the most prevalent Neurosensory disorder which is heterogenous and can also occur due to environmental causes. The majority of hearing deficiencies are of genetic origin affecting about 60% of the HI cases. A novel gene DFNB59 encodes pejvakin has been recently shown to cause deafness. This study aims to determine the frequency of DFNB59 gene mutations in coding region the gene in Bushehr province. Methods: In this descriptive experimental study, we investigated the presence of DFNB59 …

Item Type: Article
Subjects: QU Biochemistry > Cell biology and genetics
WV Otolaryngology
Divisions: Reserach Vice-Chancellar Department > Cellular and Molecular Research Center
Depositing User: zahra bagheri .
Date Deposited: 21 Nov 2017 04:59
Last Modified: 04 Feb 2018 06:02
URI: http://eprints.skums.ac.ir/id/eprint/6375

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