IMMUNOGENICITY AND EFFICACY OF THE HOSHINO STRAIN OF MUMPS (INCLUDED IN MMR VACCINE) AGAINST MUMPS IN SHAHR-E-KORD, IRAN

Sarikhani, S. and Esteghamati, A. and Kheiri, Soleiman. and Moghni, Mandana. and Hafizi, Masoud. and Avijgan, Majid. (2008) IMMUNOGENICITY AND EFFICACY OF THE HOSHINO STRAIN OF MUMPS (INCLUDED IN MMR VACCINE) AGAINST MUMPS IN SHAHR-E-KORD, IRAN. East Afr J Public Health., 93 (2S).

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Abstract

This report describes the immunogenicity and efficacy and long term immunity of Hoshino strain of Mumps (included in MMR Vaccine) in shahr-e-kord, Islamic Republic of Iran (I.R.Iran). A total of 338 Children aged 3-18 years were tested for Mumps IgG using enzyme-linked immunosorbent assay (ELISA). The proportion of susceptible, mumps IgG negative, children was 19.8% (67 subjects). Of the 67 susceptible children, 36 received the MMR vaccination and successfully completed the study. Blood was collected by venipuncture 3, 12, and 24 months after vaccination and serum samples were tested by ELISA for detection of Mumps IgM and IgG. The overall seroconversion rate was 86.1%, 77.7% and 75% at 3, 12, and 24 months after vaccination respectively.

Item Type: Article
Subjects: WC Communicable Diseases > Virus diseases
QW Microbiology and Immunology
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Pathology
Depositing User: zahra bagheri .
Date Deposited: 15 Oct 2017 07:59
Last Modified: 03 Jun 2018 05:02
URI: http://eprints.skums.ac.ir/id/eprint/5908

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