The effect of general versus spinal anesthesia on blood sugar changesduring surgery

Rajaee, Mohammad. and Pouriamofrad, Ebrahim. and Sadeghi, Bahman. and Madineh, Hossein. (2015) The effect of general versus spinal anesthesia on blood sugar changesduring surgery. Anesthesiology and Pain, 2 (8).

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Aim and Background: Stress of surgery transfers some neurological and hormonal signals which triggers some physiological responses like adrenergic stimulation, increase in noradrenalin, cortisol, growth factor, decrease in insulin and increase in insulin resistance resulting in hyperglycemia during surgery. In this study a comparison is done between general anesthesia which by blocking brain's signals decreases reactions to the stress of surgery and hyperglycemia, and spinal analgesia which blocks hormonal and adrenergic reactions by peripheral effect. Methods and Materials: This randomized control clinical trial study was performed on 60 ASA I, II patients candidate of inguinal hernioraphy. The patients were randomly allocated to general anesthesia or spinal anesthesia with T12 level. Blood sugar of the patients was measured by glucometer 1 hour before the surgery and 1 hour and 6 hours postoperatively. Findings: There was no significant difference in blood sugar levels before the surgery between two groups but it was lower 1and 6 hours postoperatively in spinal anesthesia group. Conclusions: Spinal analgesia more effectively controls rises in blood sugar during the surgery and may be a suitable alternative for general anesthesia in patients with metabolic disorders.

Item Type: Article
Uncontrolled Keywords: Keywords: stress, general anesthesia, spinal analgesia, blood sugar
Subjects: WL Nervous system
WO Surgery
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Anesthesiology
Depositing User: zahra bagheri .
Date Deposited: 11 Oct 2017 04:38
Last Modified: 17 Apr 2018 07:50

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