The effect of combination of Zingeber and Althea officinalis extracts in acute bronchitis-induced cough

Roohi Broujeni, H. and Ganji, F. and Roohi Broujeni, P. (2009) The effect of combination of Zingeber and Althea officinalis extracts in acute bronchitis-induced cough. journal of shahrekord university of medical sciences, 10 (4).


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Background and aim: Cough is a normal mechanism of respiratory system that clears the tracheobronchial tree from respiratory secretions and foreign bodies. It sometimes causes discomforts and problems in social activity of the people. One of the reasons of cough is acute bronchitis that causes inflammation of respiratory tract and persists for a few weeks. The aim of this study was to evaluate the combination effect of Zingeber and Althea officinalis to cure cough in acute bronchitis Method: In this double blind clinical trial study, we selected 60 patients who have been suffering from acute bronchitis following respiratory infections. They were divided into two groups by using a simple random sampling method. Beside their routine medications, one group (case group) was given 15 drops of both Zingeber (300 mg) and Althea officinalis (40 mg) hydro-alcoholic extracts, every 6 hours for 10 days. The second group (control group), was given placebo. After 10 days, all patients were evaluated by a questionnaire, designed by the authors, for the number of cough, night cough scores, chest pain, myalgia and retrosternal pain. Data were statistically analyzed by using t-test, χ2 and McNemar's tests. Result: A significant reduction was seen in the number of cough in both case and control groups (80% and 60%, respectively). Chest pain reports were 7.2% in case group, compared to 50% in control group (P<0.05). No significant difference was seen in muscular pain and bone pain between two groups (P>0.05). Conclusion: Hydro-alcoholic extracts of Althea offisinalis and Zingeber decrease inflammation in patient with acute bronchitis and decrease cough and acute tracheitis-induced chest pain.

Item Type: Article
Uncontrolled Keywords: Acute bronchitis, Althea Officinalis, Cough, Chest pain, Zingeber
Subjects: WF Respiratory System
QV pharmacology > QV 752 Pharmacognosy
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Internal Medicine
Reserach Vice-Chancellar Department > Cellular and Molecular Research Center
Reserach Vice-Chancellar Department > Journal of Shahrekord University of Medical Sciences
Depositing User: Users 1 not found.
Date Deposited: 09 Oct 2017 06:09
Last Modified: 09 Oct 2017 06:09

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