The effect of Nigella sativa on oxidative stress

Shariatzadeh, Seyed MohammadAli. and Malekirad, AliAkbar. and Hoveida, Reihaneh. and Rahzani, Kobra. and AghaJohary, Mehrdad. and Fazli, Davoud. (2011) The effect of Nigella sativa on oxidative stress. journal of shahrekord university of medical sciences, 12 (4).


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Background and aim: Oxidative stress is defined most simply as the imbalance between the production of free radicals and body ΄s antioxidant defense. Many medical plants contain natural antioxidant that can protect from biological system oxidative stress. The aim of this study was to determine the anti-oxidative stress of Nigella sativa. Methods: This quasi experimental study was performed on a group of 64 healthy subjects. They were invited to use the Nigella sativa (3mg/kg) twice a day for 14 days. The Blood samples before and after the study were measured for lipid per oxidation level (LPO) and total thiol molecules (TTM). Results: The results indicated a significant reduction of blood LPO (9.48±5.8 versus 6.74±5.65, P=0.008) and a significant increase in TTM plasma (0.26±0.17 versus 0.38±0.20, P=0.001). Conclusion: The present study reports that Nigella sativa has marked antioxidant activity therefore, it can reduce the amount of stress oxidative.

Item Type: Article
Uncontrolled Keywords: Antioxidant, Nigella sativa, Oxidative stress, Medical plant
Subjects: QV pharmacology > QV 752 Pharmacognosy
Divisions: Reserach Vice-Chancellar Department > Journal of Shahrekord University of Medical Sciences
Depositing User: Users 1 not found.
Date Deposited: 20 Sep 2017 05:59
Last Modified: 19 May 2018 08:12

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