Salivary levels of interleukin-8 in oral lichen planus and diabetic patients: A biochemical study

Tavangar, Atefeh and Ghalayani, Parichehr. and Abbasi Boroujeni, Mahsa. and Ghoreishian, Fereshteh Sadat. (2017) Salivary levels of interleukin-8 in oral lichen planus and diabetic patients: A biochemical study. Dental Research Journal, 14 (3). pp. 209-214.

[img]
Preview
Text
29.pdf

Download (484kB) | Preview
Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Background: This study aimed to assess the salivary levels of interleukin-8 (IL-8) in oral lichen planus (OLP) and diabetes mellitus (DM) patients, and OLP + DM patients in comparison with healthy individuals. Materials and Methods: This descriptive cross-sectional study was conducted on 75 patients (30 with OLP, 5 with both OLP and DM, 20 with DM and 20 healthy controls). The salivary levels of IL-8 and fasting blood sugar and 2-h postprandial blood glucose levels were measured in all the subjects. Data were analyzed with one-way ANOVA and post hoc least significant difference tests. Results: The mean salivary level of IL-8 was the highest in OLP + DM patients, followed by DM, OLP and control groups, respectively. Pair-wise comparisons of the groups revealed significant differences in the salivary levels of IL-8 between OLP and control, DM and control, also OLP + DM patients and control (P < 0.05). Conclusion: The increasing salivary level of IL-8 in the control, OLP, DM, OLP + DM groups, respectively, indicates the role of this inflammatory cytokine in the pathogenesis of OLP and diabetes

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: Key Words: Diabetes mellitus, interleukin-8, lichen planus, saliva
Subjects: WD Nutrition Disease and metabolic diseases
WU Dentistry. Oral surgery
Divisions: Faculty of Dentistry > Department of Periodentistry
Depositing User: zahra bagheri .
Date Deposited: 18 Sep 2017 10:19
Last Modified: 09 May 2018 04:22
URI: http://eprints.skums.ac.ir/id/eprint/5203

Actions (login required)

View Item View Item