Role of adiponectin in patients with end-stage renal failure

Beigrezaei, Sara. and Heidari, Maryam. and Tamadon, Mohammad Reza. (2017) Role of adiponectin in patients with end-stage renal failure. Koomesh, 19 (3). pp. 515-522.


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Adiponectin is a cytokine produced by the adipose tissue. This collagen-like protein has 244-amino acid and its concentration in plasma of healthy individuals is 5-40 μg / mL. In fact, adiponectin comprises 1% of the total serum protein. Although, adiponectin has anti-inflammatory and anti-atherogenic effects in physiological conditions and plays a key role in lipid and glucose metabolism and energy balance as well. However, in patients with end-stage renal disease, it is not a protector due to the changes in the structure and function, and also is considered as a risk factor. So with regard to the prevalence of atherosclerosis in patients with end stage renal disease, adiponectin may be a marker for indentifying the cardiovascular involvement of these patients.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: Keywords: Adiponectin, Atherosclerosis, Kidney Diseases, Cardiovascular Diseases, Adipose Tissue
Subjects: WG Cardiovascular System
WJ Urogenital System
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Internal Medicine
Depositing User: Users 1 not found.
Date Deposited: 18 Sep 2017 08:53
Last Modified: 16 May 2018 04:01

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