Efficacy of Passiflora incarnate on anxiety relief before orthopedic surgery: A double blinded clinical trial study

Dehghan, Morteza. and Abdoli Tafti, Abbas. and Razi, Sanaz. and Amiri, Masoud. (2016) Efficacy of Passiflora incarnate on anxiety relief before orthopedic surgery: A double blinded clinical trial study. journal of shahrekord university of medical sciences, 18 (3).


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Background and aims: Anxiety is the most prevalent feeling before surgery which could affect postoperative outcomes. Anti-anxiety properties of Passiflora incarnate have been reported in previous studies and this study was designed and conducted to determine properties of medicinal plant Passiflora incarnate on anxiety before orthopedic surgery in patients hospitalized in Ayatollah Kashani Hospital, Shahrekord. Methods: In this experimental study, 60 patients aged 25-50 years candidate for orthopedic surgery referring Ayatollah Kashani Hospital, Shahrekord were randomly assigned into two 30-individual groups of case and control. At the night before surgery, case group received oral Passiflora caerulea drop (500 mg, Passipy) and control group received placebo. On the day of surgery, by Spielberger Anxiety Inventory, the level of trait anxiety (individual anxious property) and state anxiety (individual anxious state) was recorded, and the patients' demographic characteristics were gathered by questionnaire. Results: There was no significant difference between two groups regarding to age, sex, and marital status. Mean score of state anxiety in case group (40.86±7.25) was lower than control group (50.63±4.58) (P=0.001), but mean score of trait anxiety was not significantly different between the two groups (P=0.303). Conclusion: Based on the results of this study, use of oral drop of Passiflora incarnate before orthopedic surgery helps to relieve patient's anxiety. Use of this extract is recommended for Anti-anxiety and sedative treatments.

Item Type: Article
Uncontrolled Keywords: Anxiety, Passiflora caerulea, Orthopedic surgery.
Subjects: WO Surgery
QV pharmacology > QV 752 Pharmacognosy
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Orthopedics
Reserach Vice-Chancellar Department > Journal of Shahrekord University of Medical Sciences
Reserach Vice-Chancellar Department > Medical Plants Research Center
Reserach Vice-Chancellar Department > Social Determinants of Health Research Center
Depositing User: Users 1 not found.
Date Deposited: 12 Sep 2017 08:34
Last Modified: 21 Feb 2018 10:44
URI: http://eprints.skums.ac.ir/id/eprint/4897

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