The effects of green tea extract on teratogenicity induced by low frequency electromagnetic field on bone marrow Balb/C mice embryo

Baharara, J. and Zafar Balanejad, S. and Kamareh, E. and Asadi-Samani, M. (2014) The effects of green tea extract on teratogenicity induced by low frequency electromagnetic field on bone marrow Balb/C mice embryo. Journal of HerbMed Pharmacology, 3.

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Official URL: http://www.herbmedpharmacol.com/Abstract/JHP_20150...

Abstract

<p><strong>Introduction: </strong>Electromagnetic fields produce free radicals which might be teratogen. <em>Camellia sinensis</em> is rich in natural antioxidants and antioxidants can neutralize free radicals effects. In present research the effect of<em> C. sinensis</em> extract in reduction of teratogenicity induced by electromagnetic field with 50 gauss intensity was studied on bone marrow of Balb/C mice fetuses. </p> <p><strong>Methods:</strong> In this experimental study, 24 Balb/C pregnant mice were randomly divided into four groups: control, sham exposed (off position), experimental 1 (electromagnetic field with 50-gauss intensity) and experimental 2 (treatment by <em>C. sinensis</em> extract + electromagnetic field with 50-gauss intensity). After treatment period, the bone marrow aspirates of Balb/C mice embryos were prepared and studied by Giemsa. The quantitative data were analyzed by Kruskal-Wallis and Kolmogorov- Smirnov using SPSS16 software at the level of p&lt;0.05. </p> <p><strong>Results: </strong>The mean number of promyelocytes, myelocytes, erythrocytes, necrotic and apoptotic cells in experimental group1 compared with sham exposed embryos showed significant increase but the mean number of eosinophils in experimental group 1 compared with sham exposed embryos showed significant decrease. The mean number of promyelocyte and erythrocyte in experimental group 2 compared with experimental group 1 showed significant decrease. The mean of necrotic and apoptotic cells, in experimental group 2 compared with experimental group 1 showed significant increase. </p> <p><strong>Conclusion:</strong> Usage of <em>C. sinensis</em> can decrease the damage due to teratogenicity induced by low frequency electromagnetic field in some cells.</p>

Item Type: Article
Uncontrolled Keywords: Antioxidants C. sinensis extract Bone marrow Electromagnetic field
Subjects: QT physiology
QV pharmacology > QV 752 Pharmacognosy
Divisions: Reserach Vice-Chancellar Department > Journal of Herbmed Pharmacology
Depositing User: zahra bagheri .
Date Deposited: 10 Sep 2017 06:09
Last Modified: 10 Sep 2017 06:09
URI: http://eprints.skums.ac.ir/id/eprint/4725

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