Anti-inflammatory and anti-microbial activities of aqueous leaves extract of Butea frondosa

Gupta, A. and Chaphalkar, S. (2016) Anti-inflammatory and anti-microbial activities of aqueous leaves extract of Butea frondosa. Journal of Herbmed Pharmacology, 5.

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Abstract

Introduction: Butea frondosa has been suggested to be very useful in treating inflammatory diseases but no scientific investigation has been done in such direction. In this study the anti-inflammatory and anti-microbial activities of leaves aqueous extract of B. frondosa were determined in infected and non-infected human whole blood against specific vaccine antigen, HBsAg.Methods: In order to explore the anti-inflammatory and anti-microbial activities of B. frondosa (0.5–0 mg/mL; 50 μl), infected (virally) and non infected (control) human whole blood samples were stimulated with hepatitis B vaccine containing surface antigen (HBsAg, 20 μg/mL;10 μl) in order to determined its blood counts and proliferation assay.Results: Aqueous leaves extract of B. frondosa (10 mg/mL; 50 μl) containing HBsAg inhibited the percentage count of monocytes as well as granulocytes population in both cases. In addition, this aqueous extract also reduced its proliferation rate at higher doses.Conclusion: Aqueous leaves extract of B. frondosa possesses both anti-inflammatory and antimicrobial activities and might be used for these purposes.

Item Type: Article
Uncontrolled Keywords: Butea frondosa Anti-inflammatory Anti-microbial Hepatitis B vaccine
Subjects: WC Communicable Diseases > Virus diseases
QV pharmacology > QV 752 Pharmacognosy
Divisions: Reserach Vice-Chancellar Department > Journal of Herbmed Pharmacology
Depositing User: zahra bagheri .
Date Deposited: 10 Sep 2017 03:39
Last Modified: 11 Sep 2017 03:07
URI: http://eprints.skums.ac.ir/id/eprint/4690

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