Effects of fennel, asafetida and ginseng ethanolic extracts on growth and proliferation of mouse breast cancer 4T1 cell lines

Mansourabadi, Amir Hossein. and Shams, Ali. and Mansouri, Reza. and Najafi, Ahmad. and Ajami, Maryam. (2015) Effects of fennel, asafetida and ginseng ethanolic extracts on growth and proliferation of mouse breast cancer 4T1 cell lines. Advanced Herbal Medicine, 1 (2). pp. 34-39.

[img]
Preview
Text
10.pdf

Download (74kB) | Preview
Official URL: http://herbmed.skums.ac.ir/article_12699.html

Abstract

Background: The 4T1 cells tumor growth and metastatic pattern in BALB/c mice very closely mimic human breast cancer. These herbal remedies used in traditional folk medicine have been the source of many medically beneficial drugs. The aim of the current study was to evaluate the anti-proliferative activity of the asafoetida, ginseng and fennel ethanolic extracts on mouse breast cancer 4T1 cell-line invitro.Method: in this experimental study, Asafoetida, gensing and fennel were extracted; 4T1 mouse mammary tumor cell line were cultured in 48-well flat bottom plate in density of 50x103 per well in 100 µl RPMI1640 medium then different dilutions of each extract (25 , 50, 100, 200, 500, and 2000 μg/ml) were added to cell culture. Cells then were incubated at 37 oC for 24 hours. After 24 h, cell Proliferation was determined by the BRDU assay . dataset of experiments were collected and analysed with SPSS19 software. Significant level of Data was Examined with one-way ANOVA method and P

Item Type: Article
Uncontrolled Keywords: Fennel; Asafetida; Ginseng; 4T1 Cell line; Breast Cancer
Subjects: WP Gynecology
QZ pathology-Neoplasms
QV pharmacology > QV 752 Pharmacognosy
Divisions: Reserach Vice-Chancellar Department > Advanced Herbal Medicine
Depositing User: zahra bagheri .
Date Deposited: 06 Sep 2017 04:44
Last Modified: 14 Feb 2018 08:49
URI: http://eprints.skums.ac.ir/id/eprint/4609

Actions (login required)

View Item View Item