Genetics and epidemiology of Middle East Respiratory Syndrome-Coronavirus (MERS-CoV)

Ahmadinejad, Fereshteh. and Honardoost, Mohammad Amin. and Amiri, Masoud. and Jami, Mohammad Saeid. (2015) Genetics and epidemiology of Middle East Respiratory Syndrome-Coronavirus (MERS-CoV). International Journal of Epidemiologic Research, 2 (4). pp. 204-208.

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Abstract

Background: Middle East respiratory syndrome (MERS) is a viral respiratory illness caused by a coronavirus. After the primary onset of MERS in Saudi Arabia, in September 2015 cases began to increase. The number of laboratory-affirmed cases by MERS-CoV in the Middle East has been being increased recently. Method: In this current review article, by using the terms “MERS” and “coronavirus” we first searched for English language articles in the PubMed database, published in last five years. Then by a detailed review of related articles, we provided a comprehensive information about epidemiology, genetic, host and coronavirus treatment. Result: More importantly, evidences of human-to-human transmission in Europe and America indicate that the viral adaptations in humans may precede a large-scale epidemic. The genome of Coronaviruses is a linear positive-sense single stranded large RNA and they are enveloped viruses that have a helical symmetric nucleocapsid. Some new insights have been provided in previous few months in to the animal Coronavirus hosts, transmissibility, contagion of MERS Co-V and ideal laboratory diagnostic methods. Conclusion: It seems crucial to control this new human infection “MERS-CoV” by collaborating global and local health authorities and their continual support for further research on it.

Item Type: Article
Uncontrolled Keywords: Middle East respiratory syndrome, Coronavirus, Transmission.
Subjects: WF Respiratory System
QU Biochemistry > Cell biology and genetics
Divisions: Reserach Vice-Chancellar Department > International Journal of Epidemiologic Research
Depositing User: zahra bagheri .
Date Deposited: 05 Sep 2017 09:58
Last Modified: 21 Feb 2018 10:59
URI: http://eprints.skums.ac.ir/id/eprint/4569

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