Lipids in association with leptin in maintenance hemodialysis patients

Nasri, H. and Shirani, S. and Baradaran, A. (2006) Lipids in association with leptin in maintenance hemodialysis patients. Journal of Medical Sciences, 6 (2). pp. 173-179.


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To consider the association of serum leptin with dyslipidemia in hemodialysis patients. For maintenance hemodialysis patients levels of serum pre and post dialysis blood urea nitrogen, lipid profiles and serum Leptin were measured. For the adequacy of hemodialysis the urea reduction rate was calculated. A significant difference of serum leptin between males and females of diabetics with more values in female dialysis patients was seen. In total patients a near significant and inverse correlation of serum leptin with serum LDL was seen. In male hemodialysis group a significant positive correlation of serum leptin with duration of hemodialysis and with the ages of the patients were seen, in this group also a near significant positive correlation of serum leptin with serum triglyceride levels was seen too. In total patients there was a near significant positive correlation of serum leptin with serum cholesterol of patients who had a cholesterol levels of more than 100 mg dL-1. Present data supports the hypothesis that in patients on hemodialysis, the association of leptin with cholesterol and triglyceride levels could show the positive effects of leptin on nutrition in hemodialysis patients which is in contrast to normal population.

Item Type: Article
Additional Information: cited By
Uncontrolled Keywords: calcitriol; calcium carbonate; carnitine; ferric hydroxide sucrose; folic acid; iron; leptin; low density lipoprotein; recombinant erythropoietin; triacylglycerol; vitamin B complex, adolescent; adult; aged; anemia; article; blood sampling; body mass; clinical article; controlled study; correlation analysis; diabetes mellitus; disease association; dyslipidemia; female; hemodialysis; human; hyperthyroidism; kidney failure; lipid blood level; male; protein blood level; statistical analysis; statistical significance; triacylglycerol blood level; urea nitrogen blood level
Subjects: WJ Urogenital System
QU Biochemistry > Nutrition.vitamins
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Internal Medicine
Faculty of Medicine > School of Medicine
Depositing User: zahra bagheri .
Date Deposited: 21 Aug 2017 08:34
Last Modified: 21 Aug 2017 08:34

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