Seroprevalence of hepatitis B and C virus and HIV markers among blood donors from Shahre-Kord, Iran (2004-2006)

Karimi, A. and Hoseini, S.M. (2008) Seroprevalence of hepatitis B and C virus and HIV markers among blood donors from Shahre-Kord, Iran (2004-2006). Kuwait Medical Journal, 40 (4). pp. 285-287.


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Objective: To determine the prevalence of HBV, HCV and HIV infection in voluntary blood donors from Shahre Kord, a central province of Iran, during 2004-2006 Design: Retrospective, descriptive and analytical study based on data from Serology Laboratory of the Blood Transfusion Center (BTC) at Shahre-Kord, Iran Setting: The BTC, Shahre-Kord, Iran Subjects: 35,124 apparently healthy voluntary blood donors Intervention: Detection of HBsAg, anti-HBc, anti-HCV and anti-HIV markers in blood samples using immunoenzymatic tests and Western blotting, as determined by the BTC Main Outcome Measures: Analysis of data obtained from the Serology Laboratory of the BTC, Shahre-Kord, Iran to determine prevalence Results: Overall prevalence estimates were: 0.1 for HBsAg, 0.07 for anti-HBc, 0.2 for anti-HCV and 0.002 for anti-HIV antibody. There was a statistically significant increase in the overall prevalence of HBsAg and HBcAb (from 0.015 to 0.02) and the prevalence of HCVAb (from 0.06 to 0.48) during the study period (p < 0.05). Three male donors were co-infected by HCV and HBV. Conclusion: This study suggests the need to investigate risk factors and risk groups for these infections in Iran. In the light of these results, an effective control and training program should be implemented.

Item Type: Article
Additional Information: cited By
Uncontrolled Keywords: hepatitis B core antibody; hepatitis B surface antigen; hepatitis C antibody; Human immunodeficiency virus antibody, adult; antibody detection; article; blood donor; blood transfusion; enzyme immunoassay; female; hepatitis B; Hepatitis B virus; hepatitis C; Hepatitis C virus; human; Human immunodeficiency virus; Human immunodeficiency virus infection; infection control; infection risk; Iran; major clinical study; male; mixed infection; retrospective study; seroprevalence; Western blotting
Subjects: WC Communicable Diseases > Virus diseases
WH Hemic and Lymphatic System
Divisions: Reserach Vice-Chancellar Department > Cellular and Molecular Research Center
Depositing User: zahra bagheri .
Date Deposited: 21 Aug 2017 04:07
Last Modified: 21 Aug 2017 04:07

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