Effect of lamotrigine on prophylaxis of pediatric classic migraine

Mirzaei, M.G.R. and Azimian, M. and Moezzi, M. and Vameghi, R. and Rafieian-Kopaei, M. (2009) Effect of lamotrigine on prophylaxis of pediatric classic migraine. Iranian Journal of Child Neurology, 3 (2). pp. 35-38.

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Abstract

Objective: This study was conducted to evaluate the preventive effect of lamotringine on migraine aura and migraine attacks in children, afflicted with classic migraine. Material and Methods: Conducted between October 2005 and April 2008 in the neurology clinic of Kashani hospital, Shahrekord, this study was a clinical trial, aimed at evaluating the prophylactic effects of Lamotringine administered to 21 children suffering from migraine with aura. Results: Of the subjects, 52.4 of patients were female. The most common type of aura was visual (42.9). Following use of Lamotrigine, significant reductions were seen in the frequency (from 5 ± 0.83 to 3.04 ± 1.65) and in intensity (from 6. 33 ± 1.08 to 3.66 ± 1.1) of migraine aura (P= 0.002). After 6 months of drug usage 66.6 of patients were improved. Conclusion: Lamotringine is effective in reducing the migraine aura and intensity of attacks in patients suffering from migraine with aura, and is hence beneficial for prophylactic therapy in children with classic migraine.

Item Type: Article
Additional Information: cited By
Uncontrolled Keywords: lamotrigine, adolescent; article; child; clinical article; clinical trial; drug dose increase; drug effect; drug efficacy; female; headache; human; Iran; male; migraine with aura; preschool child; prophylaxis; school child; treatment outcome
Subjects: WL Nervous system
WS Pediatrics
QV pharmacology > QV 704 Pharmaceutics
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Community Medicine
Faculty of Medicine > Department of Clinical Sciences > Department of Urology
Faculty of Medicine > Department of Clinical Sciences > Department of pharmacology
Depositing User: zahra bagheri .
Date Deposited: 21 Aug 2017 03:23
Last Modified: 21 Aug 2017 03:23
URI: http://eprints.skums.ac.ir/id/eprint/3352

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