Artichoke leaf juice contains antihypertensive effect in patients with mild hypertension

Roghani-Dehkordi, F. and Kamkhah, A.F. (2009) Artichoke leaf juice contains antihypertensive effect in patients with mild hypertension. Journal of Dietary Supplements, 6 (4). pp. 328-341.

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Abstract

Lifestyle modifications are effective for the management and prevention of hypertension. We conducted a randomized, placebocontrolled rial to evaluate the efficacy of an oral concentrated leaf juice of artichoke (Cynara scolymus L.; CS) in patients with mild hypertension ystolic blood pressure SBP/diastolic blood pressure DBP, 140-159/90-99 mmHg). Subjects were randomized into a placebo and two drug groups that received 50 and 100 mg of artichoke juice concentrate. After 12 weeks, SBP significantly reduced as compared with the baseline data in case groups and DBP was significantly lower from the baseline as compared with the placebo group. It is concluded that the use of artichoke juice concentrate may have a blood pressure-lowering effect in mild hypertension. © 2009 by Informa Healthcare USA, Inc. All rights reserved.

Item Type: Article
Additional Information: cited By
Uncontrolled Keywords: antihypertensive agent; plant medicinal product, adult; artichoke; article; blood pressure; controlled clinical trial; controlled study; drug effect; human; hypertension; male; middle aged; oral drug administration; phytotherapy; plant leaf; randomized controlled trial; treatment outcome, Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; Cynara scolymus; Humans; Hypertension; Male; Middle Aged; Phytotherapy; Plant Leaves; Plant Preparations; Treatment Outcome, Cynara scolymus
Subjects: WG Cardiovascular System
QV pharmacology > QV 752 Pharmacognosy
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Internal Medicine
Faculty of Medicine > Department of Clinical Sciences > Department of Pathology
Depositing User: zahra bagheri .
Date Deposited: 20 Aug 2017 10:01
Last Modified: 20 Aug 2017 10:01
URI: http://eprints.skums.ac.ir/id/eprint/3338

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