Polyserositis (Concato's disease) due to granulocyte colony stimulating factor therapy for lymphoma

Boroujeni, H.R. and Boroujeni, P.R. (2009) Polyserositis (Concato's disease) due to granulocyte colony stimulating factor therapy for lymphoma. Tanaffos, 8 (3). pp. 65-68.

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Abstract

Polyserositis is defined as general inflammation of serous membranes associated with serous effusion due to many causes. In this study, we evaluated polyserositis as a rare complication of GCSF therapy. A 26-year-old man with a history of lymphoma was referred to our hospital complaining of dyspnea, tachycardia, tachypnea, chest pain, bilateral pleural effusion, ascites and massive pericardial effusion after 5 days of treatment with GCSF. After 7 days of treatment with indomethacin, dexamethasone and discontinuation of GCSF, the patient improved and was referred to an oncologist for chemotherapy of lymphoma. Based on this case report, we should consider various causes of pleural effusion in a patient with lymphoma, and use drugs with caution in such patients as they may be predisposed to dyspnea and fluid retention. ©2009 NRITLD, National Research Institute of Tuberculosis and Lung Disease.

Item Type: Article
Additional Information: cited By
Uncontrolled Keywords: bleomycin; dacarbazine; dexamethasone; doxorubicin; granulocyte colony stimulating factor; indometacin; vinblastine, adult; article; ascites; cancer combination chemotherapy; cardiomegaly; case report; computer assisted tomography; Concato disease; coughing; drug withdrawal; dyspnea; follow up; human; human tissue; laboratory test; male; mixed cellularity Hodgkin lymphoma; pancytopenia; pericardial effusion; pleura biopsy; pleura effusion; polyserositis; respiratory distress; tachycardia; tachypnea; thorax pain; thorax radiography; ultrasound
Subjects: WH Hemic and Lymphatic System
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Internal Medicine
Faculty of Medicine > Department of Clinical Sciences > Department of pharmacology
Reserach Vice-Chancellar Department > Cellular and Molecular Research Center
Depositing User: zahra bagheri .
Date Deposited: 20 Aug 2017 09:45
Last Modified: 20 Aug 2017 09:45
URI: http://eprints.skums.ac.ir/id/eprint/3333

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