Does lipoprotein (a) level have a predictive value in restenosis after coronary stenting?

Khosravi, Alireza. and Pourmoghaddas, Masoud. and Ziaie, Fereshteh. and Enteshari, Arezoo. and Khaledifar, Arsalan. and Bahonar, Ahmad. (2011) Does lipoprotein (a) level have a predictive value in restenosis after coronary stenting? International Journal of Preventive Medicine, 2 (3). pp. 158-163.

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Objectives: Lipid disorders, lipoproteins, diabetes mellitus, and hypertension are the known risk factors for coronary artery diseases; however, their role is unknown in restenosis after coronary stenting. This study aimed to review the role of these factors, particularly lipoprotein (a) or Lp (a), as a predictive factor for restenosis after coronary stenting with Bare Metal Stent. Methods: In this study, coronary artery stenting was performed on 170 patients. Follow-up was done using coronary angiography in 128 patients, 6 months after conducting angioplasty. Clinical and biochemical characteristics of the patients were collected as prospective method and were compared between the patients with and without restenosis. Results: Restenosis was seen in 46 patients (35.9). Fasting blood glucose level (FBG) in patients with restenosis was significantly higher than patients without restenosis (102.3 ± 39 mg/dl vs. 84.5 ± 28.9 OR: 1.02, 95% CI: 1.00-1.04). Lp (a) levels (OR: 0.54, 95% CI: 0.26-1.10) and other biochemical markers and clinical variables had no correlation with restenosis. Conclusions: Lipoproteins and lipids may not be the underlying cause of restenosis but accurate control of diabetes may improve prognosis after elective coronary stenting.

Item Type: Article
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Uncontrolled Keywords: apolipoprotein A; apolipoprotein B; biochemical marker; glucose; high density lipoprotein cholesterol; lipoprotein A; low density lipoprotein cholesterol; triacylglycerol, adult; angiocardiography; article; bare metal stent; cholesterol blood level; clinical feature; controlled study; coronary artery obstruction; coronary stent; diabetes mellitus; digital subtraction angiography; enzyme linked immunosorbent assay; female; glucose blood level; human; laboratory test; lipoprotein blood level; major clinical study; male; percutaneous transluminal angioplasty; predictive value; prognosis; restenosis
Subjects: WG Cardiovascular System
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Cardiology
Depositing User: Users 1 not found.
Date Deposited: 20 Aug 2017 06:56
Last Modified: 05 Feb 2018 11:03

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