Prevalence of antibiotic resistance among bacteria isolates of lower respiratory tract infection in COPD Shahrekord Iran, 2005

Imani, R. and Rouhi-Boroujeni, H. and Ganji, F. (2007) Prevalence of antibiotic resistance among bacteria isolates of lower respiratory tract infection in COPD Shahrekord Iran, 2005. PAKISTAN JOURNAL OF MEDICAL SCIENCES, 23 (3, 2). pp. 438-440.

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Abstract

Background: Bacterial infection is one of the several important causes of exacerbations of chronic obstructive pulmonary disease (COPD). Antibiotic resistance has increased in all the major pathogens. The objective of this study was investigate frequency of drug resistance of species from LRTs. Methods: This cross sectional study was performed in Hajar hospital of shahrekord-Iran. Protected brush samples were obtained from the lower respiratory tract by bronchoscopy in both hospitalized and ambulatory 54 COPD patients with exacerbations yield. The in vitro susceptibilities of the isolates to 6 antimicrobial agents were then determined by the broth microditution test. Results: Among the s. pneumonia isolates tested 5.9% and 94.1% were intermediate and high level resistant to penicillin and ampicillin respectively. 58.8% of isolates were erythromycin resistance. H.influenzae isolates were 100% resistance to penicillin and ampicillin. Conclusion: Antibiotics are an important part of the treatment of COPD, suggesting that every effort should be made to conserve sensitivity of antibiotic by using them appropriately.

Item Type: Article
Uncontrolled Keywords: COPD; drug resistance; LRTIs
Subjects: WC Communicable Diseases > Infection.Bacterial Infections
WF Respiratory System
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Community Medicine
Faculty of Medicine > Department of Clinical Sciences > Department of Infectious Diseases
Depositing User: zahra bagheri .
Date Deposited: 19 Aug 2017 08:53
Last Modified: 19 Aug 2017 08:53
URI: http://eprints.skums.ac.ir/id/eprint/3168

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