Lipids in association with serum magnesium in diabetes mellitus patients

Nasri, H. and Baradaran, H.R. (2008) Lipids in association with serum magnesium in diabetes mellitus patients. BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, 109 (7). pp. 302-306.

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Abstract

Aim: To investigate whether and how serum Magnesium (Mg) concentrations influence the serum lipids in diabetes mellitus (DM) patients. The cross-sectional study was conducted on diabetic mellitus (DM) patients with various kidney functions not yet on dialysis. Patients and methods: Serum lipoprotein(a), glycosilated hemoglobin (HbA1c), serum magnesium (Mg), serum creatinine (creat), serum lipids consisting of triglycerids (Tg), cholesterol (Chol), high-density lipoprotein (HDL) were measured. Results: Study patients included 122 patients (82F, 40M). The mean patients' age was 63 ( 10) years. The mean length of time they were diabetic was 7.4 ( +/- 5.8) years (median: 6 years). The mean serum Mg was 2 (+/- 0.4) mg/dl (median: 1.99 mg/dl). The mean creatinine clearance was 64 (+/- 24) cc/min (median: 64 cc/min). In this study significant inverse correlations of serum Mg with serum cholesterol and LDL as well as nonsignificant correlations of serum Mg with serum Lp(a), HDL, Tg and with serum HgbA1c were seen. More over a significant inverse correlation of serum Mg with ages of the patients and a significant positive correlation of serum Mg with serum creatinine were seen too. Conclusions: It seems that in diabetic patients, kidney function is a key role in the regulation of serum Lp(a) levels instead of other factors like serum Mg level. Our finding further supports the importance of Mg supplementation in diabetes mellitus patients. In our study no significant correlation between serum Mg with serum HDL and Tg were found, which needs further investigation (Tab. 1, Fig. 4, Ref. 53).

Item Type: Article
Uncontrolled Keywords: serum magnesium; serum lipids; lipoprotein(a); diabetes mellitus
Subjects: WD Nutrition Disease and metabolic diseases
QU Biochemistry
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Internal Medicine
Depositing User: zahra bagheri .
Date Deposited: 19 Aug 2017 07:21
Last Modified: 19 Aug 2017 07:21
URI: http://eprints.skums.ac.ir/id/eprint/3157

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