DIFFUSING CAPACITY FOR LUNG CARBON MONOXIDE (DLCO) IN CHEMICAL LUNG INJURIES DUE TO THE USE OF MUSTARD GAS IN THE POISONED SOLDIERS OF IRAN-IRAQ WAR 2006

Rouhi-Boroujeni, H. and Ganji, F. (2010) DIFFUSING CAPACITY FOR LUNG CARBON MONOXIDE (DLCO) IN CHEMICAL LUNG INJURIES DUE TO THE USE OF MUSTARD GAS IN THE POISONED SOLDIERS OF IRAN-IRAQ WAR 2006. PAKISTAN JOURNAL OF MEDICAL SCIENCES, 26 (1). pp. 66-70.

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Abstract

Objectives: To assess the Mustard gas exposure effects on pulmonary system, particularly on diffusing capacity for lung carbon monoxide (DLCO) and simple spirometry. Methodology: Sixty-five sulfur mustard-poisoned soldiers from Mostazafan and Janbazan organization were referred to our center in 2005. Complete history, physical examination, chest X ray, Echocardiography, Arterial blood gas, high - resolution computerized tomography, diffusion capacity for lung carbon monoxide and spirometry of these were performed and compared this result with normal value. Results: The mean value of indices in studied injured subjects was: Spirometry: forced expiratory volume in one second (FEV1) = 70.4, Forced vital capacity (FVC) = 66.5, EFE 25-75=81.1, FEV1/FVC=101.9, Flow 25% = 28.7, Flow 50%=72.9, Flow 75%=100.1, Sample volume: Functional residual capacity of lungs (FRC) = 131.5, residual volume (RV) = 157.3, RV/TLC=169.1, Total lung capacity (TLC) = 91.3, KCO=131.6, TLCO=116.3. No significant correlation was observed between TLCO values with HRCT, echocardiography, ABG and spirometry values (P>0.05). Conclusion: We recommend TLCO & RV/TLV tests to assess severity of Injuries as there is no a suitable criterion to measure the real consequences of mustard gas on affected combatants. and Biological markers are also needed to determine cause-effect relations.

Item Type: Article
Uncontrolled Keywords: Mustard gas; Chemical injuries; Pulmonary function test (PFT); Diffusing capacity for lung carbon monoxide (DLCO)
Subjects: WA Public Health > Public Health Education WA.18 > WA 30 Social, Economic, and Environmental factor in public health
WA Public Health > WA 30 Social, Economic, and Environmental factor in public health
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Community Medicine
Faculty of Medicine > Department of Clinical Sciences > Department of Internal Medicine
Depositing User: zahra bagheri .
Date Deposited: 19 Aug 2017 04:49
Last Modified: 19 Aug 2017 04:49
URI: http://eprints.skums.ac.ir/id/eprint/3131

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