Relationship of venous blood gas with cervical esophagogastric anastomotic leak

Mohajeri, Gholamreza. and Tabatabaei, Abbas. and Hashemi, Mozafar. and Moazeni Bistgani, Mohammad. (2012) Relationship of venous blood gas with cervical esophagogastric anastomotic leak. Asian Cardiovascular and Thoracic Annals, 20 (5). pp. 566-569.


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Objective: this study investigated the relationship between various parameters of venous blood gas analysis of gastric fundus veins and cervical esophagogastric anastomotic leaks after transhiatal esophagectomy. Background: decreased tissue perfusion is one of the causes of anastomotic leak. There are various methods used to assess gastric conduit perfusion, with different results, and we lack a reliable method. Method: this descriptive study, performed from March 2008 to October 2010, consisted of 45 patients with esophageal cancer who underwent transhiatal esophagectomy. After gastrolysis, blood samples were taken from a gastric fundus vein and submitted for venous blood gas analysis. The cervical wounds were examined 5 days postoperatively. The patients were divided into 2 groups based on the presence of leakage, and mean values of the venous blood gas analysis were compared. Results: we observed significant differences in mean pH, PCO2, and O2 saturation between the 2 groups (p = 0.04, p = 0.03, and p = 0.04, respectively). Conclusion: venous blood gas analysis of gastric fundus veins appears to be a feasible and fast method for intraoperative assessment of microperfusion in the gastric fundus. © The Author(s) 2012.

Item Type: Article
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Uncontrolled Keywords: serum albumin; biological marker; carbon dioxide; oxygen, adenocarcinoma; adjuvant therapy; adult; alkalosis; anastomosis leakage; article; blood gas analysis; cancer patient; cancer surgery; carbon dioxide tension; cervical esophagogastric anastomotic leak; clinical article; comparative study; controlled study; descriptive research; diabetes mellitus; dysphagia; esophagus cancer; esophagus resection; female; heart disease; human; hypertension; male; oxygen saturation; pH; prospective study; respiratory failure; squamous cell carcinoma; stomach fundus; venous blood; aged; anastomosis; anastomosis leakage; blood; blood flow; esophagus resection; esophagus tumor; microcirculation; middle aged; pathophysiology; predictive value; splanchnic blood flow; stomach fundus; time; treatment outcome; vascularization; vein, Aged; Anastomosis, Surgical; Anastomotic Leak; Biological Markers; Blood Gas Analysis; Carbon Dioxide; Esophageal Neoplasms; Esophagectomy; Female; Gastric Fundus; Humans; Hydrogen-Ion Concentration; Male; Microcirculation; Middle Aged; Oxygen; Predictive Value of Tests; Prospective Studies; Regional Blood Flow; Splanchnic Circulation; Time Factors; Treatment Outcome; Veins
Subjects: WG Cardiovascular System
WI Digestive System
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Internal Medicine
Depositing User: Users 1 not found.
Date Deposited: 15 Aug 2017 08:59
Last Modified: 16 May 2018 04:45

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