Clinical manifestation and prognosis of active ocular toxoplasmosis in Iran

Kianersi, Farzan. and Naderi Beni, Afsaneh. and Naderi Beni, Zahra. (2012) Clinical manifestation and prognosis of active ocular toxoplasmosis in Iran. International Ophthalmology, 32 (6). pp. 539-545.


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Toxoplasmosis is the most common cause of posterior uveitis in the world. This study described the clinical characteristics and visual outcome of 193 patients with ocular toxoplasmosis at Feiz Hospital (Isfahan, Iran) during the last six years. The setting and design used was a retrospective non-comparative observational case series. In this study, 193 patients with ocular toxoplasmosis (111 female, 82 male) were enrolled. The distribution of symptoms and fundoscopic findings were studied. The most-reported chief complaint was blurred vision in 96 (184 patients) and floaters in 13.47 (25 patients) of cases and most frequent clinical manifestations were chorioretinitis 98.48 (190 patients), macular scars 50.7 (98 patients), and atrophic optic papilla two (1.03 ) patients. Primary retinal lesions were observed in 16 (8.2 ) and combination of active lesions and old retinochoroidal scars in 177 (91.7 ) of the patients. Retinal detachment occurred in 11 (5.69 ) patients. Bilateral involvement was found in 27 of patients. Blindness was 0.05 after treatment. Recurrence rate was 14.5 . In conclusion, ocular toxoplasmosis substantially varies among patients with different age, gender, site of lesion and other factors. Suddenly blurred vision, floater, and pain could be caused by Toxoplasma gondii. Flashing, may necessitate a more precise peripheral fundus examination. © 2012 Springer Science+Business Media B.V.

Item Type: Article
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Uncontrolled Keywords: adult; aged; article; blindness; blurred vision; case study; child; chorioretinitis; clinical feature; disease activity; epiretinal membrane; eye pain; female; human; Iran; major clinical study; male; medical record review; observational study; ophthalmoscopy; optic nerve atrophy; outcome assessment; papillitis; preschool child; prognosis; recurrent disease; retina detachment; retina macula edema; scar; toxoplasmosis; vitreous floaters; vitritis; adolescent; animal; comparative study; immunology; incidence; Iran; middle aged; prevalence; retrospective study; Toxoplasma; toxoplasmosis, antiprotozoal agent; protozoon antibody, Adolescent; Adult; Aged; Animals; Antibodies, Protozoan; Antiprotozoal Agents; Child; Child, Preschool; Female; Humans; Incidence; Iran; Male; Middle Aged; Prevalence; Retrospective Studies; Toxoplasma; Toxoplasmosis, Ocular; Young Adult
Subjects: WW Ophthalmology
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Ophthalmology
Depositing User: Users 1 not found.
Date Deposited: 15 Aug 2017 06:25
Last Modified: 29 May 2018 04:04

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