Heparin effects on mobility problems of non-hemorrhagic stroke patients

Jivad, Nahid. and Moghni, Mandana. and Azari Beni, Abbas. and Shahrifar, Maryam. and Azimian, Mojtaba. (2012) Heparin effects on mobility problems of non-hemorrhagic stroke patients. LIFE SCIENCE JOURNAL-ACTA ZHENGZHOU UNIVERSITY OVERSEAS EDITION, 9 (4). pp. 5601-5604.


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Stroke is the second leading cause of death worldwide. Ischemia is the most common cause of it which is being treated by combined therapy. One important management of acute stroke candidate for recanalization (r-TPA) that can perform for some patient with special condition in 3 to 4/5hours of onset in a few centers in Iran. there are many studies with different results regard to anti-coagulant therapy in acute stroke. The aim of this study was determination of heparin effects on mobility problems among non-hemorrhagic stroke patients. In regard of absence of diagnostic tools & teams of acute ischemic stroke treatments with r-TPA. In a double-blind randomized controlled clinical trial, 60 non-hemorrhagic stroke patients in Kashani Hospital in Shahrekord were randomly assigned in according to scale definition of NIHSS(part 5 & 6 : motor arms & legs) into two groups with same motor signs(0=no drift -1=drift -2 = cant's resist gravity-3 = no efforts against gravity-4 = no movement UN=untestable): experiment and control groups. While experiment group were subcutaneous received 5000 to 10000 unit BID every day for 3 days +aspirin 100-325 mg, control group were received only 100-325 mg aspirin. Muscular power and dyspnea & pulses of peripheral veins for evaluation of lung emboli & DVT and radiological data in CT(the first and third days) were evaluated after 3 days in two groups. There was no statistically significant difference between two groups in age, gender, power of all limbs, and duration of hospitalization. There was no significant difference between two groups in muscular power of upper and lower limbs in first day, but it was significant in the third day. In comparison of the muscular power of limbs of patients less than 55 years between two groups, there was no significant difference in the first day; however, it was significant in the third day. For patients more than 55, the significant difference was seen only in the third day in the power of left side limbs. This study recommends using heparin in non-hemorrhagic stroke patients which is more efficient than using only aspirin. Jivad N, Moghni M, Azari Beni A, Shahrifar M, Azimian M. Heparin effects on mobility problems of non-hemorrhagic stroke patients. Life Sci J 2012;9(4):5601-5604] (ISSN: 1097-8135). http://www.lifesciencesite.com. 833

Item Type: Article
Uncontrolled Keywords: Stroke; heparin; Mobility problems; non-hemorrhagic stroke patients
Subjects: WL Nervous system
QV pharmacology > QV 704 Pharmaceutics
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Neurological Diseases
Reserach Vice-Chancellar Department
Depositing User: Users 1 not found.
Date Deposited: 14 Aug 2017 07:33
Last Modified: 30 Jan 2018 06:48
URI: http://eprints.skums.ac.ir/id/eprint/2902

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