The effects of Purslane (Portulaca oleracea L.) on serum level of lipids, lipoproteins and paraoxanase 1(PON1) activity in hypercholesterolemia patients

Moradi, Mohammad-Taghi. and Gatreh Samani, Keihan. and Farrokhi, Effat. and Rafieian-Kopaei, Mahmoud. and Karimi, Ali. (2012) The effects of Purslane (Portulaca oleracea L.) on serum level of lipids, lipoproteins and paraoxanase 1(PON1) activity in hypercholesterolemia patients. LIFE SCIENCE JOURNAL-ACTA ZHENGZHOU UNIVERSITY OVERSEAS EDITION, 9 (4). pp. 5548-5552.

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Abstract

Some unverified reports around the world demonstrated that Purslane has therapeutic effects on some conditions. The aim of this study was to compare the effects of Purslane and Lovastatin therapy in decreasing serum lipids, lipoproteins, and paraoxanase1 (PON1) activity. In this clinical trial study, 93 patients with LDL-C more than 120 mg/dl who referred to the internal clinic of Kashani hospital in Sahrekord, Iran were selected and divided into two groups: Purslane (42 patients) and Lovastatin (51 patients). Fasting venous blood samples obtained before and 45 days after taking Purslane or Lovastatin, levels of all variables in the samples were measured. Our results showed that after receiving Purslane or Lovastatin serum level of cholesterol, LDL-C and OxLDL decreased. PON1 activity, ApoA1 and HDL-C increased but Triglyceride and body mass index (BMI) decreased Only in Purslane group. ApoB decreased only after taking Lovastatin. In conclusion, Purslane reduces some cardiovascular risk factors and increases PON1 activities better than Lovastatin. Moradi MT, Gatreh-Samani K, Farrokhi E, Rafieian-Koupaei M, Karimi A. The effects of Purslane (Portulaca oleracea L.) on serum level of lipids, lipoproteins and paraoxanase 1(PON1) activity in hypercholesterolemia patients. Life Sci J 2012;9(4):5548-5552] (ISSN:1097-8135). http://www.lifesciencesite.com. 823

Item Type: Article
Uncontrolled Keywords: Portulaca oleracea L.; Purslane; Paraoxanase1; Lovastatin
Subjects: QU Biochemistry
QV pharmacology > QV 752 Pharmacognosy
Divisions: Faculty of Medicine > Basic Sciences Academic Groups > Department of Microbiology
Reserach Vice-Chancellar Department > Cellular and Molecular Research Center
Reserach Vice-Chancellar Department > Medical Plants Research Center
Depositing User: zahra bagheri .
Date Deposited: 14 Aug 2017 06:51
Last Modified: 29 May 2018 09:47
URI: http://eprints.skums.ac.ir/id/eprint/2895

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