Impact of inflammation on anemia of hemodialysis patients who were under treatment of recombinant human erythropoietin.

Rafieian-Kopaei, M. and Nasri, H. (2013) Impact of inflammation on anemia of hemodialysis patients who were under treatment of recombinant human erythropoietin. Journal of renal injury prevention, 2 (3). pp. 93-5. ISSN 2345-2781

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Abstract

The aim of this study was to investigate the association between serum C-reactive protein (CRP) as the marker of inflammation with serum ferritin level and its role in the severity of anemia of hemodialysis (HD) patients. A cross-sectional study was conducted on a group of stable hemodialysis patients. There were 36 patients overall, 25 of which were non-diabetic and 11 were diabetic mean patients' age was 53 (±15.8) years. In this study, there was a significant inverse correlation between serum ferritin and hematocrit level (r=-0.34, p=0.044) (adjusted for age). Also a significant positive correlation between serum CRP and serum iron (r=0.44, p=0.008) (adjusted for age too) was observed. Moreover, in male HD patients, a significant positive correlation between serum CRP and serum ferritin (r=0.56, p=0.009) was found. Malnutrition and inflammation in hemodialysis may increase serum ferritin concentration apart from iron status, and needs more attention during iron therapy for the treatment of anemia in HD patients.

Item Type: Article
Uncontrolled Keywords: End-stage Renal Disease Ferritin Hemodialysis Anemia Malnutrition C-reactive Protein
Subjects: WH Hemic and Lymphatic System
WJ Urogenital System
QV pharmacology > QV 704 Pharmaceutics
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Urology
Reserach Vice-Chancellar Department > Medical Plants Research Center
Depositing User: Users 1 not found.
Date Deposited: 13 Aug 2017 06:26
Last Modified: 20 Aug 2017 03:58
URI: http://eprints.skums.ac.ir/id/eprint/2844

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