Association of serum lipids with level of blood pressure in type 2 diabetic patients.

Nasri, Hamid. and Behradmanesh, Saeed. and Ahmadi, Ali. and Baradaran, Azar. and Nasri, Parto. and Rafieian-Kopaei, Mahmoud. (2014) Association of serum lipids with level of blood pressure in type 2 diabetic patients. Journal of renal injury prevention, 3 (2). pp. 43-6. ISSN 2345-2781

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Abstract

INTRODUCTION Dyslipidemia and high blood pressure in diabetic patients increase the risk of microvascular and macrovascular complications. OBJECTIVES This study was conducted to investigate the association between serum lipids and level of blood pressure in type 2 diabetic patients (T2D). PATIENTS AND METHODS A prospective analytical study was carried out in 60 patients with T2D of both genders. None of the patients had a history of hypertension, and none was treated with antihypertensive drugs. Resting systolic blood pressures and fifth phase diastolic blood pressures were measured three times while the subjects were seated, and the results were averaged second and third measurements. Sixty patients with T2D were enrolled to the study. None of the patients who had a history of gout, was treated with allopurinol or treated with antihypertensive drugs previously. RESULTS Of 60 participants, mean of serum creatinine was 0.98±0.22 mg/dL. Mean of systolic and diastolic blood pressure was 133±13 mmHg and 84±7.4 mmHg respectively. In this study, a significant positive correlation of serum cholesterol with systolic (r=0.598, p=0.001) and diastolic blood pressure (r=0.584, p=0.001) was seen. Also the associations of serum LDL-C with systolic and diastolic blood pressure were as follow (r = 0.335, p<0.001) and (0.491, p<0.001) respectively. Associations of HDL-C with systolic and diastolic blood pressure were not significance as follow -0.05 and 0.04 respectively. CONCLUSION The results of this study suggest that serum cholesterol has a strong association with levels of systolic and diastolic blood pressure in T2D patients. More attention to serum lipids and treatment of dyslipidemia could halt the progress of diabetic kidney disease.

Item Type: Article
Uncontrolled Keywords: Hypertension Dyslipidemia Diabetes
Subjects: WD Nutrition Disease and metabolic diseases
WG Cardiovascular System
QU Biochemistry
Divisions: Reserach Vice-Chancellar Department > Medical Plants Research Center
Depositing User: zahra bagheri .
Date Deposited: 06 Aug 2017 05:41
Last Modified: 30 May 2018 08:17
URI: http://eprints.skums.ac.ir/id/eprint/2415

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