Comparing the patterns of hypertension and type 2 diabetes mellitus in patients with colorectal cancer

Ahmadi, A. and Hashemi-Nazari, S.-S. and Molavi-Choobini, Z. and Nasri, H. (2014) Comparing the patterns of hypertension and type 2 diabetes mellitus in patients with colorectal cancer. Journal of Isfahan Medical School, 32 (302). pp. 1537-1545.

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Abstract

Background: Type 2 diabetes mellitus (DM) and hypertension are worldwide epidemic. Colorectal cancer (CRC) is the most prevalent gastrointestinal cancer in Iran. Prevalence of type 2 diabetes mellitus and hypertension in the patients with colorectal cancer had not reported in Iran, before this study. Methods: Overall, 2570 individual-year follow-ups were conducted for 1127 patients with colorectal cancer. For diagnosis of type 2 diabetes mellitus, fasting blood sugar and glycosylated hemoglobin tests were used and for that of hypertension, blood pressure was measured in two turns. The descriptive indices were calculated and the mean and median survivals, from colorectal cancer diagnosis time, were calculated using survival analysis and the comparison among survival times was done through log-rank test. Stata12 software was used for data analysis. Findings: The prevalences of hypertension and type 2 diabetes mellitus in the patients with colorectal cancer were 13.38 (95 CI: 11.1-15.8) and 8.69 (95 CI: 7.0-10.7), respectively. Median survival time in patients with hypertension and diabetes mellitus were 8.52 and 4.90 years, respectively. According to log-rank test, no significant difference was observed between the survival time of patients with colorectal cancer suffering from hypertension and type 2 diabetes mellitus. Conclusion: The obtained findings in this study indicate that survival time in patients with type 2 diabetes mellitus is less than those with hypertension; but two metabolic diseases have same effect on survival rate of the patients with colorectal cancer. © 2014, Isfahan University of Medical Sciences(IUMS). All rights reserved.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: glycosylated hemoglobin, Article; blood pressure measurement; colorectal cancer; comparative study; follow up; glucose blood level; human; hypertension; Iran; major clinical study; non insulin dependent diabetes mellitus; prevalence; survival time
Subjects: WD Nutrition Disease and metabolic diseases
WG Cardiovascular System
WI Digestive System
QZ pathology-Neoplasms
Divisions: Faculty of Health > Department of Epidemiology
Reserach Vice-Chancellar Department
Depositing User: zahra bagheri .
Date Deposited: 05 Aug 2017 05:13
Last Modified: 05 Aug 2017 05:13
URI: http://eprints.skums.ac.ir/id/eprint/2310

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