Kooti, W. and Ghasemiboroon, M. and Asadi-Samani, M. and Ahangarpoor, A. and Zamani, M. and Amirzargar, A. and Hardani, A. (2014) The effect of Halcoholic extract of celery leaves on the delivery rate (fertilization and stillbirths), the number, weight and sex ratio of rat off spring. Advances in Environmental Biology, 8 (10). pp. 824-830.
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Abstract
Objectives: Infertility is one of the most common health problems in the world. Different plants are used in traditional medicine to treat infertility. Celery is rich in flavonoids and vitamins E and C. The present study investigated the effect of hydroalcoholic extract of celery leaves on the delivery rate, number, weight and sex ratio of rat offspring. Materials and Methods: In this experimental study, 45 Wistar rats were randomly divided into three groups of fifteen (five male and 10 female rats per group). The control group received 1 ml of distilled water, and experimental groups received respectively doses of 100 and 200 mg/kg/BW celery extract for five weeks by gavage. During the fifth week each male rat was mated with two female rats from the same group in a separate cage. After a week, every female rat was kept in the separate cages. Females received celery extract during pregnancy and until childbirth. Finally, the number of the delivery females, number, weight and sex ratio of offspring were recorded. The data were analyzed by one-way ANOVA test using SPSS15 software. Results: The number of the delivery rats in the experimental groups was not significantly different than the control group (P>0.05). The number of newborns was significantly increased in each experimental group compared to the control group (P<0.05), but the weight of infants in the experimental group receiving doses of 200 mg/kg showed a significant decrease compared to the control group (P<0.05). No significant difference was existed between the experimental and control groups in terms of sex ratio (P>0.05). Conclusions: Celery improved fertility due to have flavonoid and antioxidant activity, and its consumption in both sexes can be useful in the treatment of infertility. © 2014 AENSI Publisher All rights reserved.
| Item Type: | Article |
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| Additional Information: | cited By 29 |
| Uncontrolled Keywords: | Apium graveolens, Delivery, Sex ratio, Offspring Rat |
| Subjects: | WP Gynecology QV pharmacology > QV 752 Pharmacognosy |
| Divisions: | Reserach Vice-Chancellar Department > Medical Plants Research Center |
| Depositing User: | zahra bagheri . |
| Date Deposited: | 05 Aug 2017 03:56 |
| Last Modified: | 05 Aug 2017 03:56 |
| URI: | http://eprints.skums.ac.ir/id/eprint/2301 |
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