Association of corrected QT and QT dispersion with echocardiographic and laboratory findings in uremic patients under chronic hemodialysis

Khaledifar, A. and Momeni, A. and Hasanzadeh, K. and Amiri, M. and Sedehi, M. (2014) Association of corrected QT and QT dispersion with echocardiographic and laboratory findings in uremic patients under chronic hemodialysis. Journal of Cardiovascular Echography, 24 (3). pp. 78-82.

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Abstract

Introduction: Cardiovascular disease is the most common cause of mortality in dialysis patients. Chronic renal failure and hemodialysis (HD) patients may have longer corrected QT (QTc) interval compared with the normal population. Long QTc interval may be a predictor of ventricular arrhythmia and cardiovascular mortality in these patients and hence the aim of this study was the evaluation of the relationship between QTc interval and some echocardiographic findings and laboratory exam results in HD patients. Materials and Methods: In a cross-sectional study, 60 HD patients with age >18 years and the dialysis duration >3 months were enrolled. Blood samples were taken, and electrocardiography and echocardiography were done before the dialysis session in the patients. Results: Mean age of the patients was 56.15 ± 14.6 years. QTc interval of the patients was 0.441 ± 0.056 s and QT dispersion (QTd) was 64.17 ± 25.93 ms. There was no statistically significant relationship between QTc interval and QTd with duration of dialysis, body mass index, age, and gender (P > 0.05). There was also no significant relationship between QTc interval and QTd with mitral regurgitation, tricuspid regurgitation and aortic insufficiency (P > 0.05). In addition, QTc interval and QTd of the patients had not any correlation with serum parathormon and serum Ca, K, HCO 3 (P > 0.05). Conclusion: Based on our results, in HD patients, QTc interval and QTd were not correlated with echocardiographic findings or laboratory exam results. Therefore, it can be concluded that QTc interval prolongation probably has not any correlation with cardiac mortality of the HD patients.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: adult; aorta valve regurgitation; Article; cardiovascular disease; chronic kidney failure; cross-sectional study; dialysis; echocardiography; female; hemodialysis; human; major clinical study; male; mitral valve regurgitation; mortality; QT dispersion; QT interval; treatment duration; tricuspid valve regurgitation; uremia
Subjects: WA Public Health > WA. 900 Vital Statistics
WJ Urogenital System
Divisions: Faculty of Health > Department of Epidemiology
Faculty of Medicine > Department of Clinical Sciences > Department of Internal Medicine
Depositing User: zahra bagheri .
Date Deposited: 01 Aug 2017 09:18
Last Modified: 01 Aug 2017 09:18
URI: http://eprints.skums.ac.ir/id/eprint/2207

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