In vivo evaluation of antiparasitic effects of Artemisia abrotanum and Salvia officinalis extracts on Syphacia obvelata, Aspiculoris tetrapetra and Hymenolepis nana parasites

Amirmohammadi, M. and Khajoenia, S. and Bahmani, M. and Rafieian-Kopaei, M. and Eftekhari, Z. and Qorbani, M. (2014) In vivo evaluation of antiparasitic effects of Artemisia abrotanum and Salvia officinalis extracts on Syphacia obvelata, Aspiculoris tetrapetra and Hymenolepis nana parasites. Asian Pacific Journal of Tropical Disease, 4 (S1). S250-S254.

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Abstract

Objective: To evaluate the effects of Salvia officinalis and Artemisia abrotanum extracts against digestive system parasites of mice. Methods: The ethanol extract was prepared and dissolved in distilled water. The mebendazole was used as positive control and distilled water as negative control. After counting eggs per gram feces, infected mice with 16 eggs per gram feces contained two to three parasites of Syphacia obvelata, Aspicoloris terepetra and Hymenolipis nana designated in 4 groups. The first group was given extracts of Artemisia (150 mg/kg), the second group was given Salvia extract (150 mg/kg), the third group was given mebendazole (10 mg/kg) and finally the fourth group was given distilled water (2 mL/kg). Results: The ethanol extracts of Artemisia and Salvia plants reduced the number of parasite eggs per gram of feces. Results showed significant reduction (P-value<0.001) in the number of eggs excreted by Hymenolepis nana, Aspiculuris tetraptera, Syphacia obvelata in mice. Conclusions: These results revealed that antiparasitic effects of Artemisia and Salvia are reasonable and these two plants might be used as antiparasitic natural products. © 2014 Asian Pacific Tropical Medicine Press.

Item Type: Article
Additional Information: cited By 79
Uncontrolled Keywords: alcohol; Artemisia abrotanum extract; distilled water; mebendazole; plant extract; Salvia officinalis extract; unclassified drug, animal experiment; animal model; antiparasitic effect; Artemisia; Artemisia abrotanum; Article; Aspiculoris tetrapetra; controlled study; drug activity; drug screening; drug synthesis; feces analysis; Hymenolepis nana; in vivo study; intestine parasite; mouse; nonhuman; parasite identification; parasitosis; priority journal; Syphacia obvelata
Subjects: QV pharmacology > QV 752 Pharmacognosy
QX Parasitology
Divisions: Reserach Vice-Chancellar Department > Medical Plants Research Center
Depositing User: zahra bagheri .
Date Deposited: 01 Aug 2017 04:17
Last Modified: 01 Aug 2017 04:17
URI: http://eprints.skums.ac.ir/id/eprint/2160

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