Association of Serum Uric Acid With Level of Blood Pressure in Type 2 Diabetic Patients

Rafieian-Kopaei, M. and Behradmanesh, S. and Kheiri, S. and Nasri, H. (2014) Association of Serum Uric Acid With Level of Blood Pressure in Type 2 Diabetic Patients. IRANIAN JOURNAL OF KIDNEY DISEASES, 8 (2). pp. 152-154.

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Abstract

This study was conducted to investigate the association between serum uric acid level and blood pressure in type 2 diabetes mellitus. Sixty patients with type 2 diabetes mellitus were enrolled to the study. None of the patients had a history of gout, were treated with allopurinol, or were treated with antihypertensive drugs previously. The mean duration of DM was 9.2 +/- 4.9 years. The mean serum creatinine level was 0.98 +/- 0.22 mg/dL, and the mean serum UA level was 4.4 +/- 1.2 mg / dL. The mean protein level in 24-hour urine sample was 388 +/- 22 mg/ d. The mean systolic and diastolic blood pressure values were 133.0 +/- 13.0 mm Hg and 84.0 +/- 7.4 mm Hg, respectively. There was no significant difference in levels of serum uric acid, hemoglobin A1c, serum creatinine, proteinuria, or systolic and diastolic pressure between the men and the women. A significant positive correlation was seen between serum UA and systolic (r = 0.312, P = .02) and diastolic blood pressure (r = 0.297, P = .03). Results of this study suggest that serum uric acid had a strong association with levels of systolic and diastolic blood pressure in type 2 diabetic patients. More attention to the serum uric acid level and treatment of hyperuricemia could halt the progress of diabetic nephropathy.

Item Type: Article
Uncontrolled Keywords: type 2 diabetes mellitus; uric acid; chronic kidney disease
Subjects: WD Nutrition Disease and metabolic diseases
WG Cardiovascular System
QU Biochemistry
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Urology
Reserach Vice-Chancellar Department > Medical Plants Research Center
Depositing User: zahra bagheri .
Date Deposited: 31 Jul 2017 06:38
Last Modified: 31 Jul 2017 06:38
URI: http://eprints.skums.ac.ir/id/eprint/2112

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