Medicinal plants with hepatoprotective activity in Iranian folk medicine

Asadi-Samani, Majid. and Kafash-Farkhad, Najme. and Azimi, Nafiseh. and Fasihi, Ali. and Alinia-Ahandani., Ebrahim. and Rafieian-Kopaei, Mahmoud. (2015) Medicinal plants with hepatoprotective activity in Iranian folk medicine. Asian Pacific Journal of Tropical Biomedicine, 5 (2). pp. 146-157.


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There are a number of medicinal combinations in the Iranian traditional medicine which are commonly used as tonic for liver. In this review, we have introduced some medicinal plants that are used mainly for the treatment of liver disorders in Iranian folk medicine, with focus on their hepatoprotective effects particularly against CC14 agent. In this study, online databases including Web of Science, PubMed, Scopus, and Science Direct were searched for papers published from January 1970 to December 2013. Search terms consisted of medicinal plants, traditional medicine, folk medicine, hepatoprotective, Iran, liver, therapeutic uses, compounds, antioxidant, CC14, anti-inflammatory, and antihepatotoxic, hepatitis, alone or in combination. Allium hirtifolium Boiss., Apium graveolens L., Cynara scolymus, Berberis vulgaris L., Calendula officinalis, Nigella sativa L., Taraxacum officinale, Tragopogon porrifolius, Prangos ferulacea L., Allium sativum, Marrubium vulgare, Ammi majus L., Citrullus lanatus Thunb, Agrimonia eupatoria L. and Prunus armeniaca L. are some of the medicinal plants that have been used for the treatment of liver disorders in Iranian folk medicine. Out of several leads obtained from plants containing potential hepatoprotective agents, silymarin, β-sitosterol, betalain, neoandrographolide, phyllanthin, andrographolide, curcumin, picroside, hypophyllanthin, kutkoside, and glycyrrhizin have been demonstrated to have potent hepatoprotective properties. Despite encouraging data on possibility of new discoveries in the near future, the evidence on treating viral hepatitis or other chronic liver diseases by herbal medications is not adequate.

Item Type: Article
Additional Information: cited By 41
Uncontrolled Keywords: Agrimonia eupatoria extract; Allium hirtifolium extract; Ammi majus extract; andrographolide; Apium graveolens extract; Berberis vulgaris extract; betalain; Calendula officinalis extract; carbon tetrachloride; Citrullus lanatus extract; curcumin; Cynara scolymus extract; garlic extract; glycyrrhizic acid; hypophyllanthin; kutkoside; liver protective agent; Marrubium vulgare extract; neoandrographolide; phyllanthin; picroside; plant extract; plant medicinal product; Prangos ferulacea extract; Prunus armeniaca extract; silymarin; sitosterol; Taraxacum officinale extract; Tragopogon porrifolius extract; unclassified drug; unindexed drug, Agrimonia; Agrimonia eupatoria; Allium; Allium hirtifolium; Ammi; Ammi majus; antioxidant activity; apricot; artichoke; Article; Berberis vulgaris; black cumin; Calendula officinalis; celery; drug mechanism; flower; fruit; garlic; human; Iranian medicine; liver protection; maize; Marrubium; Marrubium vulgare; medicinal plant; nonhuman; plant leaf; plant seed; plant stem; Prangos ferulacea; Taraxacum officinale; traditional medicine; Tragopogon; Tragopogon porrifolius; watermelon, Agrimonia eupatoria; Allium hirtifolium; Allium sativum; Ammi majus; Apium graveolens; Berberis vulgaris; Calendula officinalis; Citrullus lanatus; Cynara scolymus; Marrubium vulgare; Nigella sativa; Prangos; Prunus armeniaca; Scopus; Taraxacum officinale; Tragopogon porrifolius
Subjects: WK Endocrine System
QV pharmacology > QV 752 Pharmacognosy
Divisions: Reserach Vice-Chancellar Department > Medical Plants Research Center
Depositing User: Users 1 not found.
Date Deposited: 30 Jul 2017 04:33
Last Modified: 30 Jan 2018 06:29

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