Traumatic spinal cord injury; Theranostic applications of advanced MRI techniques

Fatehi, Daryoush. and Naleini, Farhad. and Salehi, Mohammad Gharib. and Afshari, Daryoush. and Mirfendereski, Sam. and Farzizadeh, Mohammad. and Rostamzadeh, Ayoob. (2015) Traumatic spinal cord injury; Theranostic applications of advanced MRI techniques. Biomedical and Pharmacology Journal, 8 (2). pp. 891-903.

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Abstract

Imaging technology is an important part of the diagnosis and management of spinal trauma. However, many efforts have been made to develop new diagnostic biomarkers through advanced imaging techniques. Unfortunately, there is still no consensus for practical use of biomarkers in SCI patients. The authors conducted an all-encompassing literature review and relevant images were included as examples. Spinal cord and soft-tissue injuries are best evaluated by magnetic resonance imaging (MRI). However, advanced MRI techniques provide researchers with a noninvasive approach that allows evaluation of physiological and biochemical condition of the spinal cord and the brain at cellular and molecular level. The advent of new rehabilitation and treatment strategies could demand more precise and advanced techniques to approach the pathophysiology and anatomy of the spinal cord, offering more accurate and non-invasive support to research and clinical follow up.

Item Type: Article
Additional Information: cited By 4
Uncontrolled Keywords: choline; creatine; glutamic acid; glutamine; inositol; n acetylaspartic acid, Article; clinical evaluation; clinical research; diffusion tensor imaging; follow up; functional magnetic resonance imaging; human; neuroimaging; non invasive procedure; nuclear magnetic resonance imaging; nuclear magnetic resonance spectroscopy; pathophysiology; soft tissue injury; spinal cord injury
Subjects: WE Musculoskeletal system
WN Radiology . Diagnostic Imaging
Divisions: Faculty of Medicine > Basic Sciences Academic Groups > Department of Anatomy (Histology and Embryology
Faculty of Medicine > Basic Sciences Academic Groups > Department of Medical Physics
Faculty of Medicine > Department of Clinical Sciences > Department of Radiology
Depositing User: zahra bagheri .
Date Deposited: 29 Jul 2017 07:25
Last Modified: 21 May 2018 05:57
URI: http://eprints.skums.ac.ir/id/eprint/1957

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